Yamato C, Takahashi T, Fujita T
Xenobiotica. 1976 Sep;6(9):521-9. doi: 10.3109/00498257609151664.
The absorption rates are the same in rats and rabbits when [14C]trazodone HCl is injected into the duodenum of animals with pyloric vein cannulation. 2. The absorption of trazodone from the duodenum of rats is rapid in comparison with that of imipramine. 3. The residual food content of the rabbit stomach after fasting delay the overall rate of trazodone absorption by markedly decreasing transit rate from the stomach to the small intestine.
当将[14C]盐酸曲唑酮注入行幽门静脉插管的动物十二指肠时，大鼠和兔子的吸收率相同。2.与丙咪嗪相比，曲唑酮从大鼠十二指肠的吸收较快。3.禁食后兔子胃内的残余食物含量通过显著降低从胃到小肠的转运速率而延迟了曲唑酮的总体吸收速率。
