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全科医生与肺科医生对重度慢性阻塞性肺疾病住院患者的治疗比较:资源强度、医院成本和生存率。支持研究人员。了解治疗结果和风险的预后及偏好研究。

A comparison of generalist and pulmonologist care for patients hospitalized with severe chronic obstructive pulmonary disease: resource intensity, hospital costs, and survival. SUPPORT Investigators. Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatment.

作者信息

Regueiro C R, Hamel M B, Davis R B, Desbiens N, Connors A F, Phillips R S

机构信息

Department of Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA.

出版信息

Am J Med. 1998 Nov;105(5):366-72. doi: 10.1016/s0002-9343(98)00290-3.

Abstract

PURPOSE

Both generalist and pulmonologist physicians care for patients with severe chronic obstructive pulmonary disease (COPD). We studied patients hospitalized with severe COPD to explore whether supervision of care by pulmonologists is associated with greater costs or better survival.

SUBJECTS AND METHODS

We studied 866 adults with severe COPD enrolled in the Study to Understand Prognoses and Preferences for Outcomes and Risks of Treatments (SUPPORT), a prospective study at five academic medical centers. Patients were admitted to the hospital or transferred to an intensive care setting for treatment of severe COPD, defined by hypoxia (PaO2 <60 mm Hg) and hypercapnia (PaCO2 >50 mm Hg) or hypercapnia alone if on supplemental oxygen. Resource intensity was measured using a modified version of the Therapeutic Intervention Scoring System and estimated hospital costs. To account for differences in the patient case mix, propensity scores were developed to represent each patient's probability of having a pulmonologist as attending physician and each patient's probability of being in an intensive care unit (ICU) at study admission.

RESULTS

Of the 866 patients studied, 512 had generalists and 354 pulmonologists as their attending physicians. The median patient age was 70 years; 52% were male; 14% died within 30 days. After adjusting for baseline differences in patient characteristics, there were no differences in resource intensity and hospital costs in those treated by pulmonologists or generalists. Adjusted average resource intensity scores for the entire hospitalization were 16.5 for pulmonologists and 17.0 for generalists (P = 0.34). Estimated hospital costs were the same ($6,400) for patients treated by pulmonologists and generalists (P = 0.99). Patients with pulmonologists as attending physicians did not experience better survival. Comparing patients of pulmonologists to patients of generalists, the adjusted hazard ratio for 30-day mortality was 1.6 (95% confidence interval: 0.98, 2.5); the hazard ratio for 180-day mortality was 1.2 (0.9, 1.7).

CONCLUSIONS

Our findings suggest that for patients hospitalized with exacerbation of severe COPD, those with pulmonologist attending physicians do not have higher hospital resource use or better survival than those with generalist attending physicians.

摘要

目的

全科医生和肺科医生都负责治疗重度慢性阻塞性肺疾病(COPD)患者。我们对因重度COPD住院的患者进行了研究,以探讨肺科医生对治疗的监督是否与更高的费用或更好的生存率相关。

对象与方法

我们研究了866例患有重度COPD的成年人,这些患者参与了“了解治疗结果和风险的预后及偏好研究”(SUPPORT),这是一项在五个学术医疗中心进行的前瞻性研究。患者因重度COPD入院或转入重症监护病房接受治疗,重度COPD定义为低氧血症(动脉血氧分压<60 mmHg)和高碳酸血症(动脉血二氧化碳分压>50 mmHg),如果患者吸氧,则仅指高碳酸血症。使用改良版的治疗干预评分系统测量资源强度,并估算住院费用。为了考虑患者病例组合的差异,制定了倾向评分,以代表每位患者由肺科医生作为主治医生的概率以及每位患者在研究入院时进入重症监护病房(ICU)的概率。

结果

在研究的866例患者中,512例由全科医生作为主治医生,354例由肺科医生作为主治医生。患者的中位年龄为70岁;52%为男性;14%在30天内死亡。在调整患者特征的基线差异后,由肺科医生或全科医生治疗的患者在资源强度和住院费用方面没有差异。整个住院期间,肺科医生治疗患者的调整后平均资源强度评分为16.5,全科医生治疗患者的评分为17.0(P = 0.34)。肺科医生和全科医生治疗的患者估计住院费用相同(6400美元)(P = 0.99)。由肺科医生作为主治医生的患者并未有更好的生存率。将肺科医生治疗的患者与全科医生治疗的患者进行比较,30天死亡率的调整后风险比为1.6(95%置信区间:0.98,2.5);180天死亡率的风险比为1.2(0.9,1.7)。

结论

我们的研究结果表明,对于因重度COPD急性加重住院的患者,由肺科医生作为主治医生的患者与由全科医生作为主治医生的患者相比,并没有更高的医院资源使用或更好的生存率。

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