中度非酮症高血糖症——局灶性癫痫的一个病因。两例报告及文献综述。

Moderate nonketotic hyperglycemia--a cause of focal epilepsy. Report of two cases and review of literature.

作者信息

Askenasy J J, Streifler M, Carasso R

出版信息

Eur Neurol. 1977;16(1-6):51-61. doi: 10.1159/000114880.

Abstract

Nonketotic hyperglycemia has a definite convulsive effect, which may manifest itself in generalized or focal seizures. This report deals specifically with focal convulsive phenomena. Two patients with nonketotic hyperglycemia focal seizures are described. Focal seizures are of motor Jackson, aphasic, adversive or of the 'epilepsia partialis continua' type. Different types of focal seizures may appear in one and the same patient. Focal epilepsy can be the first manifestation of a diabetic disorder. Focal epileptic seizures are linked with moderate nonketotic hyperglycemia with values of 360 mg% sugar and 310 osm. Higher values lead to generalized seizures and coma. The mechanisms are discussed and pertinent literature is reviewed.

摘要

非酮症高血糖具有明确的惊厥作用，可表现为全身性或局灶性癫痫发作。本报告专门论述局灶性惊厥现象。描述了两名患有非酮症高血糖局灶性癫痫发作的患者。局灶性癫痫发作有运动性杰克逊型、失语型、转向型或“持续性部分性癫痫”型。同一患者可能出现不同类型的局灶性癫痫发作。局灶性癫痫可能是糖尿病紊乱的首发表现。局灶性癫痫发作与血糖值为360mg%、渗透压为310的中度非酮症高血糖有关。更高的值会导致全身性癫痫发作和昏迷。文中讨论了其机制并回顾了相关文献。