Nordmann J P, Brion F, Hamard P, Mouton-Chopin D
Service d'Ophtalmologie, Hôpital Tenon, Paris.
J Fr Ophtalmol. 1998 Oct;21(8):549-54.
To evaluate the new threshold strategies of the Humphrey Field Analyser, SITA Standard and SITA Fast, in normals and glaucoma patients.
Fifty healthy volunteers and 50 glaucoma patients were tested twice with three algorithms: Full Threshold, SITA Standard and SITA Fast in two sessions. The second test was taken into account to eliminate learning effect. Glaucoma patients were chosen to cover a large range of deficits. Quantitative analysis of global indexes was performed as well as qualitative comparison of visual fields by a trained optometrist.
Compared to Full Threshold, testing time was reduced by 51% in normals and 49% in glaucoma with SITA Standard and by 72% and 69% with SITA Fast, respectively. In glaucoma, mean testing time dropped from 16'01" with Full Threshold to 8'05" with SITA Standard and to 4'55" with SITA Fast. Quantitative comparison showed a high correlation between indexes (MD Full Threshold vs MD SITA Standard: r = 0.98, p < 0.01; PSD Full Threshold vs PSD SITA Standard: r = 0.94, p < 0.01). However SITA Standard and SITA Fast had a tendency to underestimate visual field defects. In glaucomatous subjects, mean MD ameliorated by 1.01 dB with SITA Standard and by 1.71 dB with SITA Fast. Mean PSD ameliorated by 0.04 dB and 0.43 dB, respectively. Qualitative analysis confirmed these last results showing artificial slight or important improvement of visual fields in 21% of the cases with SITA Standard and 30% with SITA Fast, compared to Full Threshold.
SITA Standard and SITA Fast strategies improve dramatically visual field testing time, by 51% and 72% respectively. However, one should be cautious in comparing results obtained with different algorithms, as these new strategies improve the mean defect and, to a lesser extent, the localized defect.
评估Humphrey视野分析仪的新阈值策略，即SITA标准和SITA快速策略，在正常人和青光眼患者中的应用情况。
50名健康志愿者和50名青光眼患者使用三种算法进行了两次测试：全阈值、SITA标准和SITA快速，分两个阶段进行。第二次测试用于消除学习效应。选择的青光眼患者涵盖了广泛的视野缺损范围。由训练有素的验光师对整体指标进行定量分析，并对视野进行定性比较。
与全阈值相比，SITA标准使正常人的测试时间减少了51%，青光眼患者减少了49%；SITA快速分别使正常人及青光眼患者的测试时间减少了72%和69%。在青光眼患者中，平均测试时间从全阈值时的16分01秒降至SITA标准时的8分05秒，再降至SITA快速时的4分55秒。定量比较显示各指标之间具有高度相关性（全阈值平均缺损与SITA标准平均缺损：r = 0.98，p < 0.01；全阈值模式标准差与SITA标准模式标准差：r = 0.94，p < 0.01）。然而，SITA标准和SITA快速有低估视野缺损的倾向。在青光眼患者中，SITA标准使平均缺损改善了1.01 dB，SITA快速改善了1.71 dB。平均模式标准差分别改善了0.04 dB和0.43 dB。定性分析证实了这些结果，与全阈值相比，SITA标准在21%的病例中显示视野有轻微或显著的人为改善，SITA快速在30%的病例中显示有此情况。
SITA标准和SITA快速策略分别使视野测试时间大幅缩短，分别缩短了51%和72%。然而，在比较不同算法获得的结果时应谨慎，因为这些新策略改善了平均缺损，且在较小程度上改善了局部缺损。
