Galan A R, Katzka D A, Castell D O
Gastroenterology Division, Allegheny University Hospitals, Graduate Hospital, Philadelphia, Pennsylvania, USA.
Gastroenterology. 1998 Dec;115(6):1574-6. doi: 10.1016/s0016-5085(98)70038-1.
Heterotopic gastric mucosa may occur throughout the gastrointestinal tract, including the upper esophagus. The capability of this ectopic mucosa to secrete acid has been suggested in different reports. We report for the first time a case of heterotopic gastric mucosa in the upper esophagus complicated by a stricture with secretion of acid demonstrated by prolonged ambulatory pH monitoring. Lansoprazole, 30 mg twice daily, produced symptom resolution, and repeat ambulatory pH showed complete acid suppression in the proximal esophagus.
异位胃黏膜可出现在整个胃肠道，包括食管上段。不同报告提示这种异位黏膜有分泌酸的能力。我们首次报告了1例食管上段异位胃黏膜合并狭窄且通过长时间动态pH监测证实有酸分泌的病例。兰索拉唑，每日2次，每次30毫克，症状得以缓解，再次动态pH监测显示食管近端酸分泌完全被抑制。
