Odderson I R
Department of Rehabilitation Medicine, University of Washington, Seattle, USA.
Dermatol Surg. 1998 Nov;24(11):1237-41. doi: 10.1111/j.1524-4725.1998.tb04104.x.
Hyperhidrosis, or excessive sweating, can be emotionally challenging and socially and professionally disruptive, and there have been few effective treatments. Recently, botulinum toxin has been demonstrated to be an effective treatment for hyperhidrosis of the axillae and palms and for gustatory sweating.
This article reviews the current treatments and outcomes achieved with chemodenervation of the eccrine sweat glands.
The antihydrotic response lasted 6-17 months for gustatory sweating, 2-8 months for axillary sweating, and 13 weeks to 12 months for palmar sweating.
Intracutaneous injections of botulinum toxin offer a simple, safe, and effective alternative to other conservative and surgical options.
多汗症，即出汗过多，会在情绪上带来挑战，对社交和职业造成干扰，且有效治疗方法很少。最近，肉毒杆菌毒素已被证明是治疗腋窝和手掌多汗症以及味觉性出汗的有效方法。
本文综述了目前通过对小汗腺进行化学去神经支配所取得的治疗方法和疗效。
味觉性出汗的止汗反应持续6 - 17个月，腋窝出汗持续2 - 8个月，手掌出汗持续13周至12个月。
皮内注射肉毒杆菌毒素为其他保守和手术治疗方案提供了一种简单、安全且有效的替代方法。
