Capdevila J A, Bisbe V, Gasser I, Zuazu J, Olivé T, Fernández F, Pahissa Berga A
Servicio de Enfermedades Infecciosas, Hospital General Universitari Vall d'Hebron, Universitat Autònoma, Barcelona.
Enferm Infecc Microbiol Clin. 1998 Oct;16(8):364-6.
Enterobacter amnigenus is a bacteria with doubtful pathogenicity. The observation of a patient with a well-documented E. amnigenus infection has prompted us to review the pathology caused by this microorganism.
Retrospective evaluation of the clinical charts of patients with any isolate positive for E. amnigenus over a period of 46 months. Based on the clinical data, presence or absence of other causal microorganisms and/or alternative diagnosis, E. amnigenus was classified as definitive, probable, or improbable cause of infection.
We analyzed 15 E. amnigenus isolates, representing 0.97 of 10,000, the total bacterial isolates in our laboratory for this period, and 0.52% of those corresponding to Enterobacter sp. We were able to clinically evaluate E. amnigenus in 7 patients, in whom infection by this microorganism was classified as definitive in 4, probable in 1, and improbable in 2. Antibiotic susceptibility studies showed a resistance level of 83% to ampicillin, 75% to cefazoline and cefoxitine, and 33% to amoxicillin-clavulanic acid. All isolates were susceptible to third-generation cephalosporins, aztreonam, ciprofloxacin, cotrimoxazole and aminoglycosides.
E. amnigenus cause well-documented bacterial infection in man. Thus, isolation of this microorganism should not be considered as a contaminant or simple colonizer. The clinical behavior and antimicrobial susceptibility of E. amnigenus is similar to that of E. cloacae, a taxonomically-related species.
羊水肠杆菌是一种致病性存疑的细菌。对一名有充分记录的羊水肠杆菌感染患者的观察促使我们回顾这种微生物所引起的病理学情况。
对46个月期间任何羊水肠杆菌分离株呈阳性的患者临床病历进行回顾性评估。根据临床数据、是否存在其他致病微生物和/或替代诊断，将羊水肠杆菌分类为感染的明确病因、可能病因或不太可能的病因。
我们分析了15株羊水肠杆菌分离株，占我们实验室在此期间10000株细菌分离株的0.97%，以及肠杆菌属分离株的0.52%。我们能够对7例患者进行羊水肠杆菌的临床评估，其中该微生物感染被分类为明确病因的有4例，可能病因的有1例，不太可能病因的有2例。抗生素敏感性研究显示，对氨苄西林的耐药水平为83%，对头孢唑林和头孢西丁为75%，对阿莫西林-克拉维酸为33%。所有分离株对第三代头孢菌素、氨曲南、环丙沙星、复方新诺明和氨基糖苷类均敏感。
羊水肠杆菌可在人类中引起有充分记录的细菌感染。因此，分离出这种微生物不应被视为污染物或单纯的定植菌。羊水肠杆菌的临床行为和抗菌敏感性与分类学上相关的阴沟肠杆菌相似。
