Becker N, Thomsen A B, Olsen A K, Sjøgren P, Bech P, Eriksen J
Hillerød Sygehus, H:S Rigshospitalet, Tvaerfagligt Smertecenter.
Ugeskr Laeger. 1998 Nov 16;160(47):6816-9.
This paper presents the results of a detailed study of the pain epidemiology and health related quality of life (HRQL) in 150 chronic non-malignant pain patients referred to a Danish multidisciplinary pain centre. Mean pain intensity was 71.6 (SD 18.5) on the VAS scale. HRQL was evaluated using the questionnaires: SF-36, HAD and PGWB. Compared with the normal population (NP) both physical, psychological and social well-being was severely reduced, and 58% were found to have a depressive or anxiety disorder. Sixty-three percent of the patients had neurogenic pain conditions. Of these, only 25% were treated with antidepressants or anticonvulsants. At referral 73% were treated with opioids. Mean opioid consumption was 64 mg of morphine per day. Patients had used the health care system five times more often than the NP (p < 0.001). The study showed that HRQL of chronic non-malignant pain patients is among the lowest observed for any medical condition.
本文呈现了对150名转诊至丹麦多学科疼痛中心的慢性非恶性疼痛患者的疼痛流行病学及健康相关生活质量(HRQL)进行详细研究的结果。在视觉模拟评分(VAS)量表上,平均疼痛强度为71.6(标准差18.5)。使用SF-36、医院焦虑抑郁量表(HAD)和疼痛影响问卷简表(PGWB)等问卷对HRQL进行评估。与正常人群相比,患者的生理、心理和社会幸福感均严重降低,且发现58%的患者患有抑郁或焦虑症。63%的患者患有神经源性疼痛疾病。其中,仅25%的患者接受了抗抑郁药或抗惊厥药治疗。转诊时,73%的患者接受了阿片类药物治疗。平均阿片类药物消耗量为每天64毫克吗啡。患者使用医疗保健系统的频率比正常人群高五倍(p < 0.001)。该研究表明,慢性非恶性疼痛患者的HRQL在所有医疗状况中处于最低水平。