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严重手部损伤术后连续腋路阻滞镇痛:患者自控给药与持续注射对比

[Analgesia using continuous axillary block after surgery of severe hand injuries: self-administration versus continuous injection].

作者信息

Iskandar H, Rakotondriamihary S, Dixmérias F, Binje B, Maurette P

机构信息

Département d'anesthésie-réanimation, CHU Pellegrin, Bordeaux, France.

出版信息

Ann Fr Anesth Reanim. 1998;17(9):1099-103. doi: 10.1016/s0750-7658(00)80002-7.

DOI:10.1016/s0750-7658(00)80002-7
PMID:9835978
Abstract

OBJECTIVE

To compare analgesia produced after surgery for severe hand trauma, by a continuous axillary block obtained either with a continuous injection (CA) or controlled by the patient (PCA).

STUDY DESIGN

Prospective, randomized study.

PATIENTS

Forty-two ASA physical class 1 and 2 patients were enrolled over a twelve-month period and randomly allocated either into the CA or the PCA group.

METHODS

After recovery from the surgical block, the axillary plexus was located using a nerve stimulator and a 20 G catheter (Contiplex B Braun) inserted over 5 centimeters into the axillary sheath. In the CA group (n = 21) patients received 0.1 mL.kg-1.h-1 of 0.25% bupivacaine and in the PCA group (n = 21) patients received 0.1 mL.kg-1 boluses of 0.25% bupivacaine with a one hour lock-out period. Data collected were pain intensity rated according to he visual analog scale (VAS), the total volume of bupivacaine injected, the quantity of nalbuphine administered as 10 mg boluses when VAS was = 5, and the patient's satisfaction after removal of the catheter. Statistical analysis used Student t test, ANOVA and chi 2 test.

RESULTS

The mean duration of catheter use was 5 +/- 3 days. During this period the amount of bupivacaine was significantly reduced in the PCA group when compared to the CA group (P < 0.001). Similarly, the PCA group required significantly less nalbuphine. Finally, in this group, the satisfaction index was higher than in the CA group (95 versus 52% respectively, P < 0.01).

CONCLUSION

Continuous axillary plexus blockade provides safe and effective postoperative analgesia. With the PCA technique results a lower quantity of bupivacaine is required and patient's satisfaction better.

摘要

目的

比较严重手部创伤手术后通过连续注射(CA)或患者自控(PCA)获得的腋路连续阻滞产生的镇痛效果。

研究设计

前瞻性随机研究。

患者

在十二个月期间纳入了42例美国麻醉医师协会(ASA)身体状况1级和2级的患者,并随机分为CA组或PCA组。

方法

手术阻滞恢复后,使用神经刺激器定位腋神经丛,并将一根20G导管(贝朗Contiplex B)插入腋鞘5厘米。CA组(n = 21)患者接受0.25%布比卡因0.1 mL·kg⁻¹·h⁻¹,PCA组(n = 21)患者接受0.25%布比卡因0.1 mL·kg⁻¹的推注,锁定期为1小时。收集的数据包括根据视觉模拟量表(VAS)评定的疼痛强度、布比卡因的注射总量、当VAS≥5时以10mg推注给予的纳布啡用量以及拔除导管后患者的满意度。统计分析采用学生t检验、方差分析和卡方检验。

结果

导管使用的平均时长为5±3天。在此期间,与CA组相比,PCA组的布比卡因用量显著减少(P < 0.001)。同样,PCA组所需的纳布啡明显更少。最后,该组的满意度指数高于CA组(分别为95%和52%,P < 0.01)。

结论

腋路连续神经阻滞提供安全有效的术后镇痛。采用PCA技术所需的布比卡因量更少,患者满意度更高。

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