Morita T, Kihara I, Oite T, Yamamoto T
Acta Pathol Jpn. 1976 Jul;26(4):409-22. doi: 10.1111/j.1440-1827.1976.tb00499.x.
Participation of blood born cells in rat Masugi nephritis was investigated with ultrastructural demonstration of peroxidase, in addition to conventional light and electron microscopies. Polymorphonuclear leukocytes appear immediately and transiently after injection of nephrotoxic serum. Hypercellularity in the early stage of the disease is consisted mainly of monocyte-macrophage. Proteinuria and infiltration of few monocytes are persistent through the course up to 124 days and focal sclerosis with hyaline material appears in the later stage.
除了传统的光学显微镜和电子显微镜检查外，还通过过氧化物酶的超微结构显示，研究了血源性细胞在大鼠马杉肾炎中的参与情况。注射肾毒性血清后，多形核白细胞立即短暂出现。疾病早期的细胞增多主要由单核细胞-巨噬细胞组成。蛋白尿和少量单核细胞浸润在病程长达124天的过程中持续存在，后期出现伴有透明物质的局灶性硬化。
