Rubel D M, Freeman S, Southwell I A
Skin and Cancer Foundation, Darlinghurst, New South Wales, Australia.
Australas J Dermatol. 1998 Nov;39(4):244-7. doi: 10.1111/j.1440-0960.1998.tb01482.x.
Tea tree oil is currently enjoying popularity as a 'cure-all' for a variety of skin conditions, from infections to psoriasis, and many household and personal products containing Melaleuca oil are available. However, despite its chemical complexities and enthusiastic use, there have been only a few reports of allergic reactions to tea tree oil. At the Skin and Cancer Foundation (Sydney, NSW, Australia), three of 28 normal volunteers tested strongly positive to patch testing with tea tree oil. Following further patch testing with tea tree oil constituents, all three patients reacted strongly to two preparations containing sesquiterpenoid fractions of the oil. Because patients often neglect to mention that they have used 'natural' remedies, it is important that physicians are aware of the potential adverse effects of these products. Furthermore, identification of the allergenic ingredients in tea tree oil may assist the growing industry to produce safer products.
茶树油目前作为一种治疗各种皮肤疾病的“万灵药”而备受欢迎，这些疾病涵盖从感染到牛皮癣等多种病症，市面上也有许多含有白千层油的家用和个人护理产品。然而，尽管其化学成分复杂且被广泛使用，但关于茶树油过敏反应的报道却寥寥无几。在澳大利亚新南威尔士州悉尼市的皮肤与癌症基金会，28名正常志愿者中有3人对茶树油斑贴试验呈强阳性反应。在用茶树油成分进行进一步斑贴试验后，这三名患者对两种含有该油倍半萜类成分的制剂均产生强烈反应。由于患者常常忽略提及他们使用过“天然”疗法，所以医生了解这些产品的潜在不良反应很重要。此外，确定茶树油中的致敏成分可能有助于这个不断发展的行业生产出更安全的产品。
