Rutherford Tim, Nixon Rosemary, Tam Mei, Tate Bruce
The Skin and Cancer Foundation, Melbourne, Victoria, Australia.
Australas J Dermatol. 2007 May;48(2):83-7. doi: 10.1111/j.1440-0960.2007.00341.x.
Tea tree oil use is increasing, with considerable interest in it being a 'natural' antimicrobial. It is found in many commercially available skin and hair care products in Australia. We retrospectively reviewed our patch test data at the Skin and Cancer Foundation Victoria over a 4.5-year period and identified 41 cases of positive reactions to oxidized tea tree oil of 2320 people patch-tested, giving a prevalence of 1.8%. The tea tree oil reaction was deemed relevant to the presenting dermatitis in 17 of 41 (41%) patients. Of those with positive reactions, 27 of 41 (66%) recalled prior use of tea tree oil and eight of 41 (20%) specified prior application of neat (100%) tea tree oil. Tea tree oil allergic contact dermatitis is under-reported in the literature but is sufficiently common in Australia to warrant inclusion of tea tree oil, at a concentration of 10% in petrolatum, in standard patch-test series. Given tea tree oil from freshly opened tea tree oil products elicits no or weak reactions, oxidized tea tree oil should be used for patch testing.
茶树油的使用正在增加，人们对其作为一种“天然”抗菌剂兴趣浓厚。在澳大利亚，许多市售的皮肤和头发护理产品中都含有茶树油。我们回顾性分析了维多利亚皮肤与癌症基金会在4.5年期间的斑贴试验数据，在2320例接受斑贴试验的人中，发现41例对氧化茶树油呈阳性反应，患病率为1.8%。在41例患者中，有17例（41%）的茶树油反应被认为与当前的皮炎有关。在呈阳性反应的患者中，41例中有27例（66%）回忆起之前使用过茶树油，41例中有8例（20%）明确表示之前曾涂抹过纯（100%）茶树油。茶树油过敏性接触性皮炎在文献中的报道较少，但在澳大利亚相当常见，因此应在标准斑贴试验系列中加入浓度为10%的凡士林茶树油。鉴于刚开封的茶树油产品引发的反应不明显或较弱，应使用氧化茶树油进行斑贴试验。
