Memon A, Pospula W M, Tantawy A Y, Abdul-Ghafar S, Suresh A, Al-Rowaih A
Department of Community Medicine & Behavioural Sciences, Faculty of Medicine, Kuwait University, Safat.
Int J Epidemiol. 1998 Oct;27(5):860-5. doi: 10.1093/ije/27.5.860.
Hip fracture as a consequence of osteoporosis is an important cause of morbidity and mortality among the elderly. Due to improving life expectancy, the number of elderly individuals is increasing more rapidly in the developing countries of Asia, the Middle East, Africa, and South America. Incidence of hip fracture, which rises exponentially with age, varies substantially between countries and according to the age, sex, and ethnic distribution of the population. Highest rates are observed in Scandinavia and in whites in the US, intermediate in western Europe, and the lowest rates in Asia. Little is known about the epidemiology of hip fractures in the Middle Eastern populations. In particular, there are no published reports from any of the Arab countries. We have therefore estimated the incidence of hip fracture in Kuwait and compared it with other populations.
The study was conducted at a specialized orthopaedic hospital which provides services to residents in the three governorates--representing about 70% of the total population of Kuwait. All new hip fracture patients who were operated on or treated conservatively during the 4-year period (1992-1995) were included in the study. Hip fracture was defined as clinical and radiological evidence of fracture of the proximal femur. For comparison with other populations, age-specific incidence rates in females and males aged > or =50 years were standardized to the 1985 US population.
A total of 513 cases of hip fracture (205 females, 308 males) were recorded during the study period: 293 (57.1%) cases occurred among Kuwaiti nationals and 220 (42.9%) among non-Kuwaitis (expatriates). Age-standardized rates (per 100,000) of hip fractures were, in Kuwaitis, 295 for females (95% CI: 238.8-350.8) and 200 for males (95% CI: 163.3-236.5)--much higher than those observed in other Asian countries such as Korea, Singapore, China, Malaysia, and Japan (41-202 for females, 49-100 for males). Rates in Kuwaiti females were similar to those observed in some of the European countries (Italy, UK, France) and in Asian females in the US. In contrast, rates in Kuwaiti males, which were relatively high, were almost equal to those observed in white males in the US. Rates of hip fracture in non-Kuwaitis (374 for females [95% CI: 247.6-500.8], 215 for males [95% CI: 126.5-302.9]), who predominantly (96%) originate from southeast Asian and Arab countries, were similar to those observed in Kuwaiti nationals.
The incidence of hip fracture in the Kuwaiti population is higher than that reported from other countries in Asia and is comparable to the incidence in some of the western European and North American populations.
骨质疏松导致的髋部骨折是老年人发病和死亡的重要原因。由于预期寿命的提高,亚洲、中东、非洲和南美洲的发展中国家老年人口增长更为迅速。髋部骨折的发病率随年龄呈指数上升,各国之间以及根据人口的年龄、性别和种族分布差异很大。斯堪的纳维亚半岛以及美国白人中的发病率最高,西欧居中,亚洲最低。关于中东人群髋部骨折的流行病学知之甚少。特别是,没有来自任何阿拉伯国家的公开报告。因此,我们估计了科威特髋部骨折的发病率,并与其他人群进行了比较。
该研究在一家专门的骨科医院进行,该医院为科威特三个省的居民提供服务,这三个省约占科威特总人口的70%。所有在4年期间(1992 - 1995年)接受手术或保守治疗的新髋部骨折患者均纳入研究。髋部骨折定义为股骨近端骨折的临床和放射学证据。为了与其他人群进行比较,将50岁及以上女性和男性的年龄别发病率标准化为1985年美国人口的发病率。
研究期间共记录了513例髋部骨折病例(205例女性,308例男性):293例(57.1%)发生在科威特国民中,220例(42.9%)发生在非科威特人(外籍人士)中。科威特人的髋部骨折年龄标准化发病率(每10万人),女性为295(95%可信区间:238.8 - 350.8),男性为200(95%可信区间:163.3 - 236.5),远高于韩国、新加坡、中国、马来西亚和日本等其他亚洲国家(女性为41 - 202,男性为49 - 100)。科威特女性的发病率与一些欧洲国家(意大利、英国、法国)以及美国的亚洲女性相似。相比之下,科威特男性的发病率相对较高,几乎与美国白人男性的发病率相当。非科威特人(女性为374 [95%可信区间:247.6 - 500.8],男性为215 [95%可信区间:126.5 - 302.9])的髋部骨折发病率与科威特国民相似,他们主要(9%)来自东南亚和阿拉伯国家。
科威特人群中髋部骨折的发病率高于亚洲其他国家报告的发病率,与一些西欧和北美人群的发病率相当