Kannus P, Parkkari J, Sievänen H, Heinonen A, Vuori I, Järvinen M
Accident & Trauma Research Center, UKK Institute for Health Promotion Research, Tampere, Finland.
Bone. 1996 Jan;18(1 Suppl):57S-63S. doi: 10.1016/8756-3282(95)00381-9.
There were an estimated 1.66 million hip fractures world-wide in 1990. According to the epidemiologic projections, this worldwide annual number will rise to 6.26 million by the year 2050. This rise will be in great part due to the huge increase in the elderly population of the world. However, the age-specific incidence rates of hip fractures have also increased during the recent decades and in many countries this rise has not leveled off. In the districts where this increase has either showed or leveled off, the change seems to especially concern women's cervical fractures. In men, the increase has continued unabated almost everywhere. Reasons for the age-specific increase are not known: increase in the age-adjusted incidence of falls of the elderly individuals with accompanying deterioration in the age-adjusted bone quality (strength, mineral density) may partially explain the phenomenon. The growth of the elderly population will be more marked in Asia, Latin America, the Middle East, and Africa than in Europe and North America, and it is in the former regions that the greatest increments in hip fracture are projected so that these regions will account for over 70% of the 6.26 million hip fractures in the year 2050. The incidence rates of hip fractures vary considerably from population to population and race to race but increase exponentially with age in every group. Highest incidences have been described in the whites of Northern Europe (Scandinavia) and North America. In Finland, for example, the 1991 incidence of hip fractures was 1.1% for women and 0.7% for men over 70 years of age. Among elderly nursing home residents, the figures can be as high as 6.2% and 4.9%. The lifetime risk of a hip fracture is 16%-18% in white women and 5%-6% in white men. At the age of 80 years, every fifth woman and at the age of 90 years almost every second woman has suffered a hip fracture. Since populations are aging worldwide, the mean age of the hip fracture patients are increasing rapidly, too. Between 1970 and 1991, the mean age of male Finnish patients increased dramatically from 52.9 years to 69.0 years. In women, the corresponding figures were 71.6 and 78.9 years. This change is likely to cause increasing problems in the treatment and rehabilitation of the patients. In 1990, 72% of the hip fractures worldwide occurred in women. All over the world, the hip fracture incidences are about two times higher in women than in men. Women's overrepresentation has been explained by women's lower bone mass and density and higher frequency of falling. Epidemiologic studies show that trochanteric fractures are an increasing problem since compared with cervical fractures their relative number increases progressively with age in women after the age of 60 years and since their incidence has been shown to increase in both sexes and all age groups during the recent decades. This may have direct public health implication since mortality, morbidity, and costs caused by trochanteric fractures are higher than those of the cervical fractures. Reduced bone density (strength) by age and over the recent decades has been the most frequently mentioned reason for the increase of trochanteric fractures. Also, the fall characteristics of the elderly may have changed during the recent decades resulting in increasing numbers of this type of hip fractures since the type of the hip fracture (cervical or trochanteric) also depends on the impact angle of the greater trochanter at the moment of the floor contact.
1990年,全球估计有166万例髋部骨折。根据流行病学预测,到2050年,全球每年的这一数字将增至626万。这种增长很大程度上是由于全球老年人口的大幅增加。然而,近几十年来,髋部骨折的年龄别发病率也有所上升,在许多国家,这种上升并未趋于平稳。在那些发病率上升或趋于平稳的地区,这种变化似乎尤其涉及女性的颈椎骨折。在男性中,几乎在所有地方发病率都持续上升。年龄别发病率上升的原因尚不清楚:老年个体年龄调整后的跌倒发生率增加以及伴随的年龄调整后的骨质(强度、矿物质密度)恶化可能部分解释了这一现象。亚洲、拉丁美洲、中东和非洲的老年人口增长将比欧洲和北美更为显著,预计髋部骨折增加最多的正是前几个地区,以至于到2050年,这626万例髋部骨折中,这些地区将占70%以上。髋部骨折的发病率因人群和种族而异,但在每个群体中都随年龄呈指数增长。北欧(斯堪的纳维亚)和北美的白人中发病率最高。例如,在芬兰,1991年70岁以上女性的髋部骨折发病率为1.1%,男性为0.7%。在老年养老院居民中,这一数字可能高达6.2%和4.9%。白人女性一生中髋部骨折的风险为16% - 18%,白人男性为5% - 6%。在80岁时,每五名女性中就有一名曾发生髋部骨折,在90岁时,几乎每两名女性中就有一名曾发生髋部骨折。由于全球人口老龄化,髋部骨折患者的平均年龄也在迅速增加。1970年至1991年期间,芬兰男性患者的平均年龄从52.9岁急剧增至69.0岁。女性的相应数字分别为71.6岁和78.9岁。这种变化可能会给患者的治疗和康复带来越来越多的问题。1990年,全球72%的髋部骨折发生在女性身上。在世界各地,女性的髋部骨折发病率约为男性的两倍。女性占比过高的原因是女性骨量和骨密度较低以及跌倒频率较高。流行病学研究表明,转子间骨折问题日益严重,因为与颈椎骨折相比,60岁以后女性转子间骨折的相对数量随年龄逐渐增加,而且近几十年来其发病率在男女各年龄组中均有所上升。这可能对公共卫生有直接影响,因为转子间骨折导致的死亡率、发病率和成本高于颈椎骨折。年龄增长以及近几十年来骨密度(强度)降低是转子间骨折增加最常被提及的原因。此外,近几十年来老年人的跌倒特征可能发生了变化,导致这种类型的髋部骨折数量增加,因为髋部骨折的类型(颈椎或转子间)也取决于大转子在接触地面瞬间的撞击角度。