Ikeda Y, Koyanagi N, Mori M, Minagawa S, Toyomasu T, Ezaki T, Tateishi H, Sugimachi K
Department of Surgery II, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Hepatogastroenterology. 1998 Sep-Oct;45(23):1535-8.
BACKGROUND/AIMS: Although the incidence of proximal colon cancer is known to increase with age, the prognosis of proximal colon cancer remains unclear.
One thousand two hundred and five patients with colorectal cancer were analyzed with regard to tumor location, age and Duke's stage.
When Duke's stage was compared with tumor location, an advanced Duke's stage was found more frequently in the proximal colon than in the distal colorectum (p<0.01). In Duke's A colorectal cancer, the incidence of tumors limited to within the submucosal layer decreased from 73.1% in patients under 65 years of age to 60.9% in patients over 65 years of age.
Since advanced stage cancer was more frequently found in the proximal colon than in the distal colorectum, careful examination for the early detection of proximal colon cancer, particularly in the elderly, is called for.
背景/目的：尽管已知近端结肠癌的发病率随年龄增长而增加，但其预后仍不明确。
对1205例结直肠癌患者的肿瘤位置、年龄和杜克分期进行了分析。
将杜克分期与肿瘤位置进行比较时，发现近端结肠中晚期杜克分期的比例高于远端结直肠（p<0.01）。在杜克A期结直肠癌中，局限于黏膜下层的肿瘤发生率从65岁以下患者的73.1%降至65岁以上患者的60.9%。
由于近端结肠中晚期癌症的发现频率高于远端结直肠，因此需要对近端结肠癌进行仔细检查以实现早期检测，尤其是对老年人。
