Kovács T, Hargitai A, Kovács K L, Mécs I
Department of Biotechnology, A. József University of Szeged, Hungary.
FEMS Microbiol Lett. 1998 Aug 15;165(2):323-8. doi: 10.1111/j.1574-6968.1998.tb13164.x.
The expression of the sigB gene of Bacillus subtilis was analysed in response to a mild acid shock. This gene is subject to sigmaB-dependent regulation. It has been found that the expression of sigB is induced as part of the acid-tolerant response. In that respect sigB is similar to the previously described gene gsiB which is also a member of the sigmaB regulon. Through this induction, the sigmaB regulon provides protection against acid shock. Besides its protective role against acid shock, no other general function could be directly associated with the sigmaB regulon. An acidification of the cytoplasmic environment induces synthesis of general stress proteins in B. subtilis.
分析了枯草芽孢杆菌sigB基因在轻度酸休克反应中的表达情况。该基因受σB依赖性调控。已发现sigB的表达作为耐酸反应的一部分被诱导。在这方面，sigB与先前描述的基因gsiB相似，gsiB也是σB调节子的成员。通过这种诱导，σB调节子提供了对酸休克的保护。除了其对酸休克的保护作用外，没有其他一般功能可直接与σB调节子相关联。细胞质环境的酸化会诱导枯草芽孢杆菌中一般应激蛋白的合成。
