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杂种犬和灵缇犬对星状神经节刺激的血流动力学反应。

Hemodynamic responses to stellate ganglion stimulation in mongrels and greyhounds.

作者信息

Cox R H, Peterson L H, Detweiler D K

出版信息

Am J Physiol. 1976 Oct;231(4):1062-7. doi: 10.1152/ajplegacy.1976.231.4.1062.

Abstract

A comparison of the effects of left stellate ganglion stimulation (SGS) on central and aortic hemodynamics has been made in chloralose-anesthetized mongrel (M), and greyhound (GH) dogs. Measurements of aortic pressure and flow, and left ventricular pressure were made during stimulation of the decentralized left SG at different frequencies from 0 to 20 Hz. The increases in aortic pressure and flow with SGS were larger in the GH, especially for low frequencies of stimulation. Stroke volume was increased with SGS in the GH at all stimulation rates, whereas in the M it was unchanged. A greater decrease in left ventricular end-diastolic pressure with SGS was found in the GH. These results suggest that differences exist in both the intrinsic and extrinsic control of cardiac output in the greyhound dog compared to the mongrel. These differences may be in part responsible for the elevated arterial blood pressure in the greyhound compared to the mongrel.

摘要

在水合氯醛麻醉的杂种犬(M)和灵缇犬(GH)中,比较了左侧星状神经节刺激(SGS)对中心和主动脉血流动力学的影响。在以0至20 Hz的不同频率刺激去神经支配的左侧星状神经节期间,测量了主动脉压力和流量以及左心室压力。SGS引起的主动脉压力和流量增加在灵缇犬中更大,尤其是在低频刺激时。在所有刺激频率下,SGS均可使灵缇犬的每搏输出量增加,而杂种犬则无变化。灵缇犬在SGS时左心室舒张末期压力的下降幅度更大。这些结果表明,与杂种犬相比,灵缇犬的心输出量内在和外在控制均存在差异。这些差异可能部分导致了灵缇犬与杂种犬相比动脉血压升高。

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