Aloi F, Solaroli C, Paradiso M, Formiconi A
Dipartimento di Discipline Medico Chirurgiche, Università degli Studi, Torino.
Minerva Urol Nefrol. 1998 Sep;50(3):205-8.
Skin metastasis from transitional cell carcinoma of the urinary bladder is quite uncommon. Especially, the inflammatory type of skin metastasis with features of carcinoma erysipeloid is a rare event.
A 65-year-old man with bladder carcinoma who underwent radical cystectomy developed 6 months later red to violaceous papules, indurated plaques and edema in the perigenital area. The initial presumptive diagnosis was irritative contact dermatitis and cellulitis. Histologic examination of a skin biopsy disclosed dilated lymphatic vessels filled with neoplastic cells resembling transitional cells.
Although carcinoma erypeloid is most commonly caused by breast carcinoma, it has also been linked to other carcinomas. Dermal lymphatic involvement is an essential feature shared by cases of inflammatory carcinoma.
Carcinoma erysipeloid may be caused by bladder carcinoma. Skin metastases are generally present in the late stages of this disease and indicate a poor outcome.
膀胱移行细胞癌的皮肤转移相当罕见。特别是具有癌性丹毒样特征的炎症型皮肤转移更是罕见。
一名65岁的膀胱癌男性患者，在接受根治性膀胱切除术后6个月，在生殖器周围区域出现了从红色到紫红色的丘疹、硬结性斑块和水肿。最初的初步诊断为刺激性接触性皮炎和蜂窝织炎。皮肤活检的组织学检查显示扩张的淋巴管内充满了类似移行细胞的肿瘤细胞。
虽然癌性丹毒最常见由乳腺癌引起，但也与其他癌症有关。真皮淋巴管受累是炎症性癌病例共有的一个基本特征。
癌性丹毒可能由膀胱癌引起。皮肤转移通常出现在该疾病的晚期，提示预后不良。
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