Takubo K, Mafune K, Tanaka Y, Sasajima K
Department of Clinical Pathology, Tokyo Metropolitan Institute of Gerontology, Japan.
Nihon Geka Gakkai Zasshi. 1998 Sep;99(9):547-51.
Defining the cardia as consisting of 2 cm of the distal esophagus and 2 cm of the proximal stomach, we describe the detailed histopathological features of the cardia and esophagogastric junction (EGJ). The distance between the EGJ and the squamocolumnar junction (SCJ) was 0-10 mm (mean: 3 mm) in 50 Japanese autopsy cases, but the SCJ was not located below the EGJ. It has been reported that pancreatic metaplasia, small leiomyomas, inflammatory EGJ polyps, carditis, and Barrett's epithelium are often recognizable in the cardia, and the literature on these conditions is reviewed. The relationship between leiomyomas and gastrointestinal stromal tumors is also reviewed, and the histopathology of short-segment Barrett's esophagus is described. In biopsy specimens obtained from Barrett's esophagus, the presence of ducts of esophageal glands proper in the metaplastic mucosa as revealed by microscopy can be used to establish the diagnosis, although only in a short-segment of Barrett's esophagus less than 3 cm in length. Finally, several English and Japanese textbooks on the pathology of the digestive tract containing descriptions of normal and diseased cardia are described for the convenience of authors writing scientific papers on diseases of the cardia.
将贲门定义为由远端食管的2厘米和近端胃的2厘米组成，我们描述了贲门和食管胃交界（EGJ）的详细组织病理学特征。在50例日本尸检病例中，EGJ与鳞柱状交界（SCJ）之间的距离为0 - 10毫米（平均：3毫米），但SCJ未位于EGJ下方。据报道，胰腺化生、小平滑肌瘤、炎性EGJ息肉、贲门炎和巴雷特上皮在贲门中常常可以识别，本文对这些情况的相关文献进行了综述。还综述了平滑肌瘤与胃肠道间质瘤之间的关系，并描述了短节段巴雷特食管的组织病理学。在从巴雷特食管获取的活检标本中，显微镜下显示化生黏膜中存在食管固有腺管可用于确诊，不过仅适用于长度小于3厘米的短节段巴雷特食管。最后，为方便撰写关于贲门疾病科学论文的作者，介绍了几本包含正常和患病贲门描述的英文和日文消化道病理学教科书。
