Niehaus L, Gottschalk S, Weber U
Neurologische Kliniken der Charité, Berlin.
Ultraschall Med. 1998 Oct;19(5):225-9. doi: 10.1055/s-2007-1000495.
The Müller-Casty flow index (FI) is recommended for use in transcranial Doppler sonography (TCD) to measure relative changes in volume flow. We examined the ability of the FI to assess the volume flow during diameter changes of basal cerebral arteries.
Nitroglycerin (NTG) was used to induce dilation of basal cerebral arteries without affecting cerebral blood flow. Transverse and sagittal sections of the middle cerebral artery (MCA) were obtained by magnetic resonance imaging (MRI) and blood flow velocities in the MCA were measured by TCD. The FI was calculated by multiplying Doppler shift frequency and signal power.
NTG induced an increase of MCA-diameter in MRI. The mean FI remained approximately constant (-2.6 +/- 6%), while the mean blood flow velocity dropped significantly (-15 +/- 6%).
The FI can be used to estimate volume flow in basal cerebral arteries even in case of diameter change.
推荐使用米勒 - 卡斯蒂血流指数（FI）进行经颅多普勒超声检查（TCD），以测量血流体积的相对变化。我们研究了FI在评估基底脑动脉直径变化时血流体积的能力。
使用硝酸甘油（NTG）诱导基底脑动脉扩张，同时不影响脑血流量。通过磁共振成像（MRI）获得大脑中动脉（MCA）的横断和矢状面图像，并通过TCD测量MCA中的血流速度。FI通过将多普勒频移频率与信号功率相乘来计算。
在MRI中，NTG导致MCA直径增加。平均FI保持大致恒定（-2.6 +/- 6%），而平均血流速度显著下降（-15 +/- 6%）。
即使在直径变化的情况下，FI也可用于估计基底脑动脉中的血流体积。
