Bonfiglioli C, De Berti G, Nichelli P, Nicoletti R, Castiello U
Dipartimento di Psicologia, Universita' di Bologna, European Medical Center, Italy.
Neuropsychologia. 1998 Nov;36(11):1203-8. doi: 10.1016/s0028-3932(97)00171-1.
This experiment investigates the kinematic characteristics of the reach to grasp movement of Parkinson's and Huntington's disease subjects under two different experimental conditions. In the first condition subjects were required to perform the movement at a normal speed, while in the second condition they were required to perform the movement as fast as possible. Results showed that the kinematic parameterization of movement in Parkinson's disease subjects did not differ from that of age-matched control subjects for both the normal and the fast condition. However, the performances of Huntington's disease subjects appeared to be different when compared to the other two groups. Differences were mainly related to Huntington's disease patients' inability to properly define the temporal features of the movements.
本实验研究了帕金森病和亨廷顿舞蹈病患者在两种不同实验条件下抓握动作的运动学特征。在第一种条件下,受试者被要求以正常速度执行动作,而在第二种条件下,他们被要求尽可能快地执行动作。结果表明,帕金森病患者在正常和快速条件下的运动学参数化与年龄匹配的对照组受试者没有差异。然而,与其他两组相比,亨廷顿舞蹈病患者的表现似乎有所不同。差异主要与亨廷顿舞蹈病患者无法正确定义动作的时间特征有关。