Kovacs S O, Kovacs S C
Laser and Skin Surgery Center of New York, New York, USA.
J Am Acad Dermatol. 1998 Dec;39(6):899-920; quiz 921-2. doi: 10.1016/s0190-9622(98)70263-4.
Dermatomyositis is a rare inflammatory myopathy with characteristic skin manifestations and muscular weakness. The disease can be categorized as adult idiopathic, juvenile, or amyopathic dermatomyositis as well as that associated with a connective tissue disease or a malignancy. Immunologic factors are most likely involved in the pathogenesis of the disease; however, genetic and environmental issues may also play important roles. Treatment with immunosuppressive agents has proved successful in the majority of patients, although significant morbidity still occurs.
皮肌炎是一种罕见的炎症性肌病，具有特征性的皮肤表现和肌肉无力。该疾病可分为成人特发性、青少年型或无肌病性皮肌炎，以及与结缔组织病或恶性肿瘤相关的皮肌炎。免疫因素很可能参与了该疾病的发病机制；然而，遗传和环境因素也可能起重要作用。尽管仍有显著的发病率，但免疫抑制剂治疗已被证明在大多数患者中是成功的。
