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Selective degeneration of sudomotor fibers in Ross syndrome and successful treatment of compensatory hyperhidrosis with botulinum toxin.

作者信息

Bergmann I, Dauphin M, Naumann M, Flachenecker P, Müllges W, Koltzenburg M, Sommer C

机构信息

Neurologische Universitätsklinik, Würzburg, Germany.

出版信息

Muscle Nerve. 1998 Dec;21(12):1790-3. doi: 10.1002/(sici)1097-4598(199812)21:12<1790::aid-mus26>3.0.co;2-i.

DOI:10.1002/(sici)1097-4598(199812)21:12<1790::aid-mus26>3.0.co;2-i
PMID:9843086
Abstract

We report a 5-year follow-up of a patient with Ross syndrome. A biopsy of the anhidrotic skin immunostained with protein gene product 9.5 visualized by confocal microscopy revealed selective loss of sudomotor fibers, whereas epidermal innervation remained intact, providing the first morphologic evidence of selective loss of sudomotor fibers in this syndrome. Among the different treatment strategies employed for the patient's disabling segmental hyperhidrosis, intracutaneous injection of botulinum toxin A was the most helpful.

摘要

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