Holzinger F, Schilling M, Z'graggen K, Stain S, Baer H U
Department of Visceral and Transplantation Surgery (Chairman: Prof. M.W. Büchler), Inselspital, University of Bern, Switzerland.
Dig Surg. 1998;15(3):273-8. doi: 10.1159/000018628.
Only 34 cases of primary cystic duct carcinoma have previously been published in the literature. Most of these cases presented with upper abdominal pain and a palpable mass in the right upper quadrant due to gallbladder hydrops or cholecystitis. We report a case of cystic duct carcinoma with the clinical presentation of obstructive jaundice. The patient was treated by cholecystectomy, resection of the common bile duct and a Roux-en-Y hepaticojejunostomy. An extended lymph node dissection was not performed. Fourteen months after the operation the patient died with local carcinoma recurrence. A literature review comparing clinical signs, surgical treatment, and outcome of 14 Japanese and 21 reported Western cases, including ours, was performed. Extended lymph node dissection in addition to combined resection of the gallbladder and ductus hepaticocholedochus appears to offer a better prognosis and larger survival, including the chance of potential cure.
此前文献中仅发表过34例原发性胆囊管癌。这些病例大多因胆囊积水或胆囊炎而出现上腹部疼痛以及右上腹可触及肿块。我们报告1例以梗阻性黄疸为临床表现的胆囊管癌病例。该患者接受了胆囊切除术、胆总管切除术及Roux-en-Y肝空肠吻合术。未进行扩大淋巴结清扫术。术后14个月,患者因局部癌复发死亡。我们对14例日本病例及包括我们的病例在内的21例报告的西方病例进行了文献综述,比较了其临床体征、手术治疗及预后情况。除了联合切除胆囊和肝外胆管外,扩大淋巴结清扫术似乎能带来更好的预后和更长的生存期,包括潜在治愈的机会。