Toohill R J, Martinelli D L, Janowak M C
Ann Otol Rhinol Laryngol. 1976 Sep-Oct;85(5 Pt.1):600-8. doi: 10.1177/000348947608500506.
Autogenous nasal septal grafts were utilized in 18 dogs. The availability, method of transfer, placement, take, stability and long-term survival of these grafts are presented. Transfer of septal cartilage or composite grafts of nasal mucosa and cartilage to surgically created defects of cricoid and thyroid cartilage was performed on eight animals. Ten animals had composite grafts three months after stenosing procedures. Results were excellent in all grafts to the cricoid and subglottic areas. Grafts to the thyroid and glottic regions were characterized by severe resorption of cartilage and fibrosis. Composite grafts to the glottic area were successful in improving the airway. Results are documented by microlaryngeal photographs and histologic sections. A literature review accompanies the presentation with emphasis on clinical utilization of composite nasal septal grafts. Twelve previously reported cases of repair by this method for laryngeal and upper tracheal stenosis are discussed. A patient with severe traumatic laryngeal stenosis successfully rehabilitated is added to this list and details the clinical value of these grafts.
18只犬采用自体鼻中隔移植物。本文介绍了这些移植物的可用性、转移方法、放置、成活、稳定性和长期存活情况。对8只动物进行鼻中隔软骨或鼻黏膜与软骨复合移植物转移至手术造成的环状软骨和甲状软骨缺损处的操作。10只动物在狭窄手术后3个月进行复合移植物植入。所有植入环状软骨和声门下区域的移植物效果良好。植入甲状腺和声门区域的移植物表现为软骨严重吸收和纤维化。声门区域的复合移植物成功改善了气道。结果通过显微喉镜照片和组织学切片记录。本文还进行了文献综述，重点介绍了复合鼻中隔移植物的临床应用。讨论了此前报道的12例采用该方法修复喉和上气管狭窄的病例。新增了1例严重创伤性喉狭窄患者成功康复的病例，并详细说明了这些移植物的临床价值。
