Giannacopoulos K Ch, Hatzidaki E G, Papanicolaou N C, Relakis K J, Kokori H G, Giannacopoulou C C
Gynecological Department, LAIKO General Hospital, Athens, Greece.
Eur J Obstet Gynecol Reprod Biol. 1998 Oct;80(2):227-9. doi: 10.1016/s0301-2115(98)00112-2.
The incidence of HIV-associated tuberculosis is increasing worldwide, especially in developing countries. HIV infected patients rapidly develop clinically significant disease, respond poorly to complete treatment and present with extrapulmonary tuberculosis. Although a relative increase of genital tuberculosis would be expected, this has not been reported. Probably, tuberculous systemic disease is diagnosed earlier, before genital tuberculosis occur. The present study is a report of case of a young African female patient, who was admitted with symptoms of acute pelvic inflammatory disease due to genital tuberculosis and proved to be HIV infected. The patient was managed by intravenous antibiotic administration, but since no clinical or laboratory improvement was achieved, a laparotomy and salpingooophorectomy was performed. Histopathology revealed tuberculosis and after that the patient proved to be HIV infected. Further investigation did not reveal pulmonary or other extragenital manifestation of tuberculosis. The only manifestation of HIV infection and genital tuberculosis was the symptoms of an acute pelvic inflammatory disease, which is extremely rare.
全球范围内，与艾滋病病毒相关的结核病发病率正在上升，尤其是在发展中国家。感染艾滋病病毒的患者会迅速发展为具有临床意义的疾病，对全程治疗反应不佳，并伴有肺外结核。虽然预计生殖器结核的发病率会相对增加，但尚未有相关报道。可能是在生殖器结核发生之前，结核全身性疾病就更早被诊断出来了。本研究报告了一例年轻的非洲女性患者，她因生殖器结核出现急性盆腔炎症状入院，后被证实感染了艾滋病病毒。该患者接受了静脉抗生素治疗，但由于未取得临床或实验室改善，遂进行了剖腹手术及输卵管卵巢切除术。组织病理学显示为结核病，之后该患者被证实感染了艾滋病病毒。进一步检查未发现肺部或其他生殖器外的结核表现。艾滋病病毒感染和生殖器结核的唯一表现是急性盆腔炎症状，这极为罕见。
