MitBASE：一个全面且集成的线粒体DNA数据库。

MitBASE: a comprehensive and integrated mitochondrial DNA database.

作者信息

Attimonelli M, Altamura N, Benne R, Boyen C, Brennicke A, Carone A, Cooper J M, D'Elia D, de Montalvo A, de Pinto B, De Robertis M, Golik P, Grienenberger J M, Knoop V, Lanave C, Lazowska J, Lemagnen A, Malladi B S, Memeo F, Monnerot M, Pilbout S, Schapira A H, Sloof P, Slonimski P, Saccone C

机构信息

Dipartimento di Biochimica e Biologia Molecolare, Università degli Studi di Bari, 70126 Bari, Italy.

出版信息

Nucleic Acids Res. 1999 Jan 1;27(1):128-33. doi: 10.1093/nar/27.1.128.

DOI:10.1093/nar/27.1.128

PMID:9847157

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC148112/

Abstract

MitBASE is an integrated and comprehensive database of mitochondrial DNA data which collects all available information from different organisms and from intraspecie variants and mutants. Research institutions from different countries are involved, each in charge of developing, collecting and annotating data for the organisms they are specialised in. The design of the actual structure of the database and its implementation in a user-friendly format are the care of the European Bioinformatics Institute. The database can be accessed on the Web at the following address: http://www.ebi.ac. uk/htbin/Mitbase/mitbase.pl. The impact of this project is intended for both basic and applied research. The study of mitochondrial genetic diseases and mitochondrial DNA intraspecie diversity are key topics in several biotechnological fields. The database has been funded within the EU Biotechnology programme.

摘要

MitBASE是一个综合性线粒体DNA数据库，收集了来自不同生物体以及种内变体和突变体的所有可用信息。不同国家的研究机构参与其中，各自负责开发、收集和注释他们所专长的生物体的数据。数据库实际结构的设计及其以用户友好格式的实现由欧洲生物信息学研究所负责。可通过以下网址在网上访问该数据库：http://www.ebi.ac.uk/htbin/Mitbase/mitbase.pl。该项目的影响旨在用于基础研究和应用研究。线粒体遗传疾病和线粒体DNA种内多样性的研究是几个生物技术领域的关键课题。该数据库由欧盟生物技术计划资助。