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创伤患者的体温过低

Hypothermia in trauma patients.

作者信息

Segers M J, Diephuis J C, van Kesteren R G, van der Werken C

机构信息

Department of Surgery, University Hospital Vrije Universiteit, Amsterdam, The Netherlands.

出版信息

Unfallchirurg. 1998 Oct;101(10):742-9.

PMID:9847700
Abstract

Accidental hypothermia (AH) can be defined as an unintentional decrease in core temperature below 35 degrees C during cold exposure by individuals without intrinsic thermoregulatory dysfunction. Pathophysiological changes can be attributed both to the severity of hypothermia and to co-morbid factors such as trauma, submersion, intoxication and underlying diseases. In trauma victims stratified according to the Injury Severity Score, the factor hypothermia is considered to be a poor prognostic sign for survival. In these patients rewarming therapy should be applied as soon as possible. In the Utrecht University Hospital, adult patients with AH are managed according to an algorithm based on their presenting hemodynamic conditions. Patients with perfusing cardiac rhythms and systolic pressures over 80 mmHg will receive continuous arteriovenous rewarming (CAVR). Arrested and hemodynamically instable patients are treated with cardiopulmonary bypass (CPB). In a 3-year period, 22 patients with AH were admitted to the emergency department. Fourteen patients had a trauma as the cause of hypothermia. Twenty patients were treated according to the algorithm (CAVR n = 18, CPB n = 2) and two patients were alternatively managed. Mortality in the CAVR group was 28% and total mortality reached 32%. Complications of CAVR are related to placement and removal of vascular catheters and may be severe in these patients with impaired coagulation. CAVR permits a good access to the (trauma-) patient and rewarming can be continued synchronously with diagnosis and treatment of various injuries.

摘要

意外低温(AH)可定义为在寒冷暴露期间,无内在体温调节功能障碍的个体核心体温意外降至35摄氏度以下。病理生理变化既归因于低温的严重程度,也归因于合并因素,如创伤、溺水、中毒和基础疾病。在根据损伤严重程度评分分层的创伤患者中,低温因素被认为是生存预后不良的标志。对于这些患者,应尽快进行复温治疗。在乌得勒支大学医院,成年AH患者根据其就诊时的血流动力学状况按照一种算法进行处理。有灌注心律且收缩压超过80 mmHg的患者将接受持续动静脉复温(CAVR)。心脏骤停和血流动力学不稳定的患者采用体外循环(CPB)治疗。在3年期间,22例AH患者被收入急诊科。14例患者因创伤导致低温。20例患者按照算法进行治疗(CAVR 18例,CPB 2例),另外2例患者采用其他方式处理。CAVR组的死亡率为28%,总死亡率达到32%。CAVR的并发症与血管导管的置入和拔除有关,在这些凝血功能受损的患者中可能很严重。CAVR便于接触(创伤)患者,复温可与各种损伤的诊断和治疗同步进行。

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