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[辐射动物淋巴细胞中的DNA合成受促细胞分裂剂和葡萄球菌抗原的影响]

[DNA synthesis in lymphocytes of irradiated animals as affected by mitogens and Staphylococcal antigens].

作者信息

Kholodna L S, Pozur V K, Liubchenko T A, Hritsenko L M, Holeva O H, Kucherenko M Ie

机构信息

T.Shevchenko University, Kyiv, Ukraine.

出版信息

Ukr Biokhim Zh (1978). 1998 Jan-Feb;70(1):58-62.

PMID:9848141
Abstract

Proliferation activity of lymphocytes from rats was studied using micromethod of blast transformation reaction after exposure of X-ray irradiation (absorbed doses for animals are 0.5 and 1 Gr). The reducing of the functional activity of lymphocytes was found. There was difference in lymphocyte response induced by standard mitogens (PHA, ConA, LPS) and antigens of Staphylococcus protein A and peptidoglycan. The irradiation protective effects of Staphylococcus substances were found.

摘要

采用微量法检测X射线照射(动物吸收剂量为0.5和1戈瑞)后大鼠淋巴细胞的增殖活性。结果发现淋巴细胞的功能活性降低。标准促有丝分裂原(PHA、ConA、LPS)以及金黄色葡萄球菌蛋白A和肽聚糖抗原诱导的淋巴细胞反应存在差异。还发现了金黄色葡萄球菌物质的辐射防护作用。

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