Bondarenko L B
Institute of Pharmacology and Toxicology, Academy of Medical Sciences of Ukraine, Kyiv.
Ukr Biokhim Zh (1978). 1998 May-Jun;70(3):12-23.
Collagen constitutes approximately one third of the body's proteins; it has different functions, and changes in its metabolism and structure accompany almost every pathologic process. This article reviews basic knowledge of the alterations and defects in collagen metabolism and structure which give rise to a number of heritable and acquired diseases, their causes and consequences.
胶原蛋白约占人体蛋白质的三分之一;它具有多种功能,几乎每种病理过程都伴随着其代谢和结构的变化。本文综述了胶原蛋白代谢和结构的改变与缺陷的基础知识,这些改变与缺陷会引发多种遗传性和后天性疾病及其病因和后果。