[Bone and bone related biochemical examinations. Bone and collagen related metabolites. Structure and metabolisms of collagen].

Collagens are the most abundant proteins in mammals. They are the major structural proteins in bone as well as other organs. The synthesis of collagens is regulated by numerous growth factors, cytokines and hormones. The higher structure of collagen is derived from the series of biosynthesis including its characteristic primary amino acid structure and post-translational modifications. The degradation products of collagen have been utilized as markers for bone turnover.