Brugha R, Heptonstall J, Farrington P, Andren S, Perry K, Parry J
Immunisation Division, Public Health Laboratory Service, Communicable Disease Surveillance Centre, London, UK.
Occup Environ Med. 1998 Aug;55(8):567-9. doi: 10.1136/oem.55.8.567.
To evaluate the risk of hepatitis A virus (HAV) infection among sewage workers from occupational exposure to raw sewage.
An analytical cross sectional study of 241 company employees with possible occupational exposure to sewage in a large water and sewerage company was carried out. Previous exposure to hepatitis A virus infection was assessed, as were its associations with possible risk factors.
Frequent occupational exposure to raw sewage was a significant risk factor for HAV infection, independently of other known risk factors (odds ratio 3.73, 95% confidence interval 1.48 to 9.37). Of 50 employees who reported occupational exposure to raw sewage most of the time, 30 (60%) had had HAV infection.
Employees who are likely to be at risk of frequent exposure should have their immunity ensured. The salivary assay for IgG anti-HAV used in the study was highly specific and would be suitable for prevaccination testing of older employees, who are more likely to be immune.
评估污水工人因职业接触未经处理的污水而感染甲型肝炎病毒(HAV)的风险。
对一家大型供水和污水处理公司中241名可能职业接触污水的公司员工进行了一项分析性横断面研究。评估了既往甲型肝炎病毒感染情况及其与可能的风险因素的关联。
频繁职业接触未经处理的污水是HAV感染的一个重要风险因素,独立于其他已知风险因素(比值比3.73,95%置信区间1.48至9.37)。在50名报告大部分时间职业接触未经处理污水的员工中,30名(60%)曾感染HAV。
可能频繁接触风险的员工应确保其免疫力。研究中使用的IgG抗-HAV唾液检测具有高度特异性,适用于对更可能具有免疫力的年长员工进行接种前检测。