Heng B H, Goh K T, Doraisingham S, Quek G H
Institute of Environmental Epidemiology, Ministry of the Environment, Singapore.
Epidemiol Infect. 1994 Aug;113(1):121-8. doi: 10.1017/s0950268800051530.
To determine whether or not occupational exposure to sewage is associated with a higher seroprevalence of hepatitis A virus (HAV) infection, 600 sewage workers in Singapore were tested for total (IgG and IgM) antibody to HAV by enzyme immunoassay. Using logistic regression with stepwise procedure, the adjusted seroprevalence of sewage workers was 2.2 times higher than that of another non-occupationally exposed population group. Seroprevalence was significantly correlated with age and educational levels, the association being independent of the occupational association. The epidemiological data in the study show that sewage workers have an increased occupational risk of acquiring HAV infection and should be protected by active immunization.
为了确定职业性接触污水是否与甲型肝炎病毒（HAV）感染的血清阳性率较高有关，对新加坡的600名污水工人进行了酶免疫测定，以检测其针对HAV的总抗体（IgG和IgM）。采用逐步回归的逻辑回归分析，污水工人的校正血清阳性率比另一个非职业性接触人群组高2.2倍。血清阳性率与年龄和教育水平显著相关，这种关联独立于职业关联。该研究中的流行病学数据表明，污水工人感染HAV的职业风险增加，应通过主动免疫进行保护。
