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晶状体混浊的种族差异:索尔兹伯里眼评估(SEE)项目。

Racial differences in lens opacities: the Salisbury Eye Evaluation (SEE) project.

作者信息

West S K, Muñoz B, Schein O D, Duncan D D, Rubin G S

机构信息

Dana Center for Preventive Ophthalmology, Wilmer Eye Institute, The Johns Hopkins Hospital, Baltimore, MD, USA.

出版信息

Am J Epidemiol. 1998 Dec 1;148(11):1033-9. doi: 10.1093/oxfordjournals.aje.a009579.

Abstract

The purpose of this study was to determine racial differences in the prevalence of different types of lens opacities and cataract surgery. Between 1993 and 1995, the Salisbury Eye Evaluation (SEE) Project enrolled a representative sample of 2,520 community-dwelling persons aged 65-84 years in Salisbury, Maryland, 26.4% of whom were African-American. Participants received a full eye examination, and photographs were taken for documentation of lens status. Photographs were graded using a standardized grading system for the presence of cortical, nuclear, or posterior subcapsular cataract (PSC) opacification in at least one eye. The odds of having cortical opacities were 4.0 times greater among African Americans than among Caucasians (95% confidence interval (CI) 3.3-4.8). Caucasians were significantly more likely to have nuclear opacities (odds ratio = 2.1, 95% CI 1.7-2.6) and PSC opacities (odds ratio = 2.5, 95% CI 1.7-3.6). The odds of cataract surgery were 2.8 times higher among Caucasians, but these differences did not explain the differences in the prevalence of different types of lens opacities by racial group. With lower rates of nuclear and PSC opacities than Caucasians, African Americans may have a lower demand for cataract surgery. However, even with these differences, there is still significant unnecessary loss of vision due to cataract among older African Americans, for whom programs to ensure access to surgical care are indicated.

摘要

本研究的目的是确定不同类型晶状体混浊的患病率及白内障手术方面的种族差异。1993年至1995年期间,索尔兹伯里眼评估(SEE)项目在马里兰州索尔兹伯里招募了2520名年龄在65 - 84岁的社区居民作为代表性样本,其中26.4%为非裔美国人。参与者接受了全面的眼部检查,并拍摄照片以记录晶状体状态。照片使用标准化分级系统进行分级,以确定至少一只眼中是否存在皮质性、核性或后囊下白内障(PSC)混浊。非裔美国人出现皮质性混浊的几率是白种人的4.0倍(95%置信区间(CI)3.3 - 4.8)。白种人患核性混浊(优势比 = 2.1,95% CI 1.7 - 2.6)和PSC混浊(优势比 = 2.5,95% CI 1.7 - 3.6)的可能性显著更高。白种人进行白内障手术的几率高出2.8倍,但这些差异并不能解释不同种族群体中不同类型晶状体混浊患病率的差异。由于非裔美国人的核性和PSC混浊发生率低于白种人,他们对白内障手术的需求可能较低。然而,即便存在这些差异,老年非裔美国人中仍有大量因白内障导致的不必要视力丧失,因此需要开展相关项目以确保他们能够获得手术治疗。

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