甲状腺乳头状癌的大滤泡变体。1例细针穿刺活检结果报告。
Macrofollicular variant of papillary thyroid carcinoma. Report of a case with fine needle aspiration biopsy findings.
作者信息
Hirokawa M, Shimizu M, Terayama K, Kanahara T, Sonoo H, Manabe T
机构信息
Department of Pathology, Kawasaki Medical School, Kurashiki, Japan.
出版信息
Acta Cytol. 1998 Nov-Dec;42(6):1441-3. doi: 10.1159/000332182.
BACKGROUND
Macrofollicular variant of papillary thyroid carcinoma is defined as a combination of numerous macrofollicles occupying 50% of the tumor and foci of the conventional follicular variant of papillary carcinoma. To the best of our knowledge, there have been no English-language reports on its cytologic findings.
CASE
A fine needle aspiration specimen from a mass of the thyroid in a 59-year-old female showed a large collection of dense, inspissated colloid and a few sheets of tumor cells with nuclei characteristic of papillary carcinoma. There were no three-dimensional, branching papillae with fibrovascular cores.
CONCLUSION
Although macrofollicular variant of papillary carcinoma is very rare, fine needle aspiration cytology may contribute to its correct diagnosis.
背景
甲状腺乳头状癌的大滤泡变体被定义为众多大滤泡占肿瘤的50% 与乳头状癌传统滤泡变体灶的组合。据我们所知，尚无关于其细胞学表现的英文报道。
病例
一名59岁女性甲状腺肿块的细针穿刺标本显示大量浓稠、浓缩的胶体以及几片具有乳头状癌特征性细胞核的肿瘤细胞。未见有纤维血管轴心的三维分支乳头。
结论
尽管乳头状癌的大滤泡变体非常罕见，但细针穿刺细胞学检查可能有助于其正确诊断。
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