Hecht P, Hayashi K, Cooley A J, Lu Y, Fanton G S, Thabit G, Markel M D
Comparative Orthopaedic Research Laboratory, School of Veterinary Medicine, University of Wisconsin-Madison 53706, USA.
Am J Sports Med. 1998 Nov-Dec;26(6):808-14. doi: 10.1177/03635465980260061201.
The purpose of this in vivo study was to analyze the short-term tissue response of joint capsule to monopolar radiofrequency energy and to compare the effects of five power settings at 65 degrees C on heat distribution in joint capsule. In 12 mature Hampshire sheep, the medial and lateral aspects of both stifles were treated with monopolar radiofrequency energy under arthroscopic control in a single uniform pass to the synovial surface. The radiofrequency generator power settings were 0, 10, 15, 20, 25, and 30 watts (N = 8/group). The electrode tip temperature was 65 degrees C. Histologic analysis at 7 days after surgery revealed thermal damage of capsule at all radiofrequency power settings. The lesion's cross-sectional area, depth, vascularity, and inflammation were commensurate with radiofrequency power. Tissue damage was indicated by variable inflammatory cell infiltration, fusion of collagen, pyknosis of fibroblasts, myonecrosis, and vascular thrombosis, whereas synovial hyperplasia, fibroblast proliferation, and rowing of sarcolemmal nuclei demonstrated regenerative processes. This study revealed that radiofrequency power settings and heat loss through lavage solution play a significant role in heat distribution and morphologic alterations in joint capsule after arthroscopic application of monopolar radiofrequency energy.
本体内研究的目的是分析关节囊对单极射频能量的短期组织反应，并比较65摄氏度下五种功率设置对关节囊内热量分布的影响。在12只成年汉普郡绵羊中，在关节镜控制下，通过单次均匀穿刺至滑膜表面，对双侧膝关节的内侧和外侧进行单极射频能量治疗。射频发生器的功率设置为0、10、15、20、25和30瓦（每组N = 8）。电极尖端温度为65摄氏度。术后7天的组织学分析显示，在所有射频功率设置下，关节囊均有热损伤。病变的横截面积、深度、血管分布和炎症程度与射频功率相当。组织损伤表现为不同程度的炎性细胞浸润、胶原融合、成纤维细胞固缩、肌坏死和血管血栓形成，而滑膜增生、成纤维细胞增殖和肌膜细胞核排列则显示有再生过程。本研究表明，射频功率设置和灌洗液导致的热量损失在关节镜下应用单极射频能量后关节囊的热量分布和形态学改变中起重要作用。
