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招募具有精神分裂症谱系人格症状的非患者志愿者。

Recruitment of non-patient volunteers with schizophrenia spectrum personality symptoms.

作者信息

Kunkel R, Adami H, Zetlmeisl M, Ross D, Thaker G

机构信息

Schizophrenia Related Disorders Program, Maryland Psychiatric Research Center, Baltimore, MD 21228, USA.

出版信息

Schizophr Res. 1998 Nov 30;34(3):181-6. doi: 10.1016/s0920-9964(98)00102-9.

DOI:10.1016/s0920-9964(98)00102-9
PMID:9850984
Abstract

Authors aimed to evaluate the yield and effectiveness of recruiting community schizophrenia spectrum personality (SSP) subjects via targeted newspaper advertisements listing SSP traits. Eight newspaper advertisements listing SSP traits were placed in regional newspapers over a 3-year period. Respondents (n = 209) were screened thoroughly via telephone, and eligible subjects were invited for face-to-face clinical interviews. One hundred and one subjects (48% of the respondents) were screened out over the phone and another 30% were no-shows or refused. Of the 46 subjects who were interviewed, a majority (24 subjects; 52%) met this study's criteria for SSP. These subjects experienced significant psychotic-like symptoms, as ascertained by a self-rating scale, and showed a downward drift in their socio-economic status. One can successfully recruit SSP subjects, with high yield, using targeted telephone advertisements combined with thorough telephone screening.

摘要

作者旨在评估通过列出精神分裂症谱系人格(SSP)特征的有针对性的报纸广告招募社区SSP受试者的成功率和有效性。在三年时间里,在地区报纸上刊登了八则列出SSP特征的报纸广告。通过电话对受访者(n = 209)进行了全面筛查,并邀请符合条件的受试者进行面对面临床访谈。101名受试者(占受访者的48%)在电话筛查中被排除,另有30%未到场或拒绝。在接受访谈的46名受试者中,大多数(24名受试者;52%)符合本研究的SSP标准。通过自评量表确定,这些受试者经历了明显的类似精神病的症状,并且其社会经济地位呈下降趋势。使用有针对性的电话广告并结合全面的电话筛查,可以成功且高效地招募到SSP受试者。

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Spatial working memory as a cognitive endophenotype of schizophrenia: assessing risk for pathophysiological dysfunction.空间工作记忆作为精神分裂症的一种认知内表型:评估病理生理功能障碍的风险。
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Clinical, cognitive, and social characteristics of a sample of neuroleptic-naive persons with schizotypal personality disorder.
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Schizophr Res. 2005 Oct 15;78(2-3):297-308. doi: 10.1016/j.schres.2005.05.016.
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A model of smooth pursuit eye movement deficit associated with the schizophrenia phenotype.一种与精神分裂症表型相关的平稳跟踪眼球运动缺陷模型。
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