Yoshida T, Aramaki M, Matsumoto T, Morii Y, Sasaki A, Kitano S
Department of Surgery I, Oita Medical University, Hasama, Japan.
Int Surg. 1998 Apr-Jun;83(2):124-7.
From 1995 to 1996, 20 patients with carcinoma of the distal bile duct (Bi) and 16 with carcinoma of the pancreatic head (Ph) underwent pancreaticoduodenectomy or total pancreatectomy with systematic extended lymphadenectomy. Histopathological specimens were examined with special reference to nodal metastases. Pancreatic parenchymal invasion was present in 10 of 20 patients with Bi. The frequency of nodal involvement in Bi with pancreatic invasion and Ph was significantly greater than in Bi without pancreatic invasion (p<0.05 and p<0.01, respectively). Metastasis to nodes around the superior mesenteric artery or abdominal aorta in Bi with pancreatic invasion occurred more frequently than in Bi without pancreatic invasion (p<0.05), though was not different from the frequency observed in Ph. The pattern of lymphatic spread in distal bile duct carcinoma with pancreatic invasion was practically equal to the mode in carcinoma of the pancreatic head.
1995年至1996年，20例远端胆管癌（Bi）患者和16例胰头癌（Ph）患者接受了胰十二指肠切除术或全胰切除术，并进行了系统性扩大淋巴结清扫。对组织病理学标本进行检查，特别关注淋巴结转移情况。20例Bi患者中有10例存在胰腺实质侵犯。伴有胰腺侵犯的Bi和Ph患者的淋巴结受累频率显著高于无胰腺侵犯的Bi患者（分别为p<0.05和p<0.01）。伴有胰腺侵犯的Bi患者中，肠系膜上动脉或腹主动脉周围淋巴结转移的发生率高于无胰腺侵犯的Bi患者（p<0.05），但与Ph患者的发生率无差异。伴有胰腺侵犯的远端胆管癌的淋巴转移模式与胰头癌的模式基本相同。
