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用于治疗与房间隔缺损相关的心房颤动的迷宫手术

Maze procedure for atrial fibrillation associated with atrial septal defect.

作者信息

Kobayashi J, Yamamoto F, Nakano K, Sasako Y, Kitamura S, Kosakai Y

机构信息

Department of Cardiovascular Surgery, National Cardiovascular Center, Osaka, Japan.

出版信息

Circulation. 1998 Nov 10;98(19 Suppl):II399-402.

PMID:9852933
Abstract

BACKGROUND

Atrial fibrillation (AF) is a relatively common complication in elderly patients with an atrial septal defect (ASD). However, use of the simultaneous maze procedure for AF associated with ASD remains controversial. We examined the efficacy and risk of the use of the maze procedure in these patients.

METHODS AND RESULTS

Between March 1992 and April 1997, 26 patients underwent the maze procedure as a concomitant operation with ASD closure (maze group). Kosakai's modified maze procedure was performed in 17 patients, the modified Cox maze II or III procedure was performed in 6, and the restrictive right-sided maze procedure was performed in 3. The mean +/- SD age at surgery was 58.2 +/- 9.1 years. The mean +/- SD duration of AF was 7.8 +/- 8.5 years. The mean +/- SD left atrial dimension was 47 +/- 9 mm, and 24 patients (92%) had a larger-than-normal (> 35 mm) left atrium. The mean +/- SD follow-up period was 2.7 +/- 1.7 years. There were no hospital or late deaths. There was no thromboembolic episode in the late follow-up period. Sinus rhythm was regained in all patients who underwent conventional the right- and left-sided maze procedure except for 1 patient. However, 3 patients who underwent the restrictive right-sided maze procedure showed a return to AF rhythm. The atrial A wave was detected with the use of pulsed Doppler study in all patients who had a restored sinus rhythm. During the same period, 45 patients who were > 40 years old and without AF underwent only ASD closure (control group). The incidence of reopening the chest for bleeding was significantly (P = 0.046) higher in the maze group (12%) than in the control group (0%). Paroxysmal AF more frequently (P = 0.023) occurred in the control group (18%) than in the maze group (0%).

CONCLUSIONS

These results suggest that the standard maze procedure should be considered in patients with AF associated with ASD. The restrictive right-sided maze procedure was not reliable, probably due to preoperative enlargement of the left atrium.

摘要

背景

心房颤动(AF)是老年房间隔缺损(ASD)患者相对常见的并发症。然而,迷宫手术同步用于ASD相关的AF仍存在争议。我们研究了迷宫手术在这些患者中的疗效和风险。

方法与结果

1992年3月至1997年4月期间,26例患者在ASD封堵术的同时接受了迷宫手术(迷宫组)。17例患者采用小坂改良迷宫手术,6例采用改良Cox迷宫II或III手术,3例采用限制性右侧迷宫手术。手术时的平均年龄±标准差为58.2±9.1岁。AF的平均持续时间±标准差为7.8±8.5年。左心房平均直径±标准差为47±9mm,24例患者(92%)左心房大于正常(>35mm)。平均随访时间±标准差为2.7±1.7年。无住院或晚期死亡病例。晚期随访期间无血栓栓塞事件。除1例患者外,所有接受传统左右侧迷宫手术的患者均恢复窦性心律。然而,3例接受限制性右侧迷宫手术的患者恢复为AF心律。在所有恢复窦性心律的患者中,使用脉冲多普勒研究检测到心房A波。同期,45例年龄>40岁且无AF的患者仅接受了ASD封堵术(对照组)。迷宫组(12%)再次开胸止血的发生率显著高于对照组(0%)(P = 0.046)。对照组(18%)阵发性AF的发生率高于迷宫组(0%)(P = 0.023)。

结论

这些结果表明,对于ASD相关的AF患者应考虑采用标准迷宫手术。限制性右侧迷宫手术不可靠,可能是由于术前左心房扩大。

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