对乙酰氨基酚吸收技术在液体胃排空率研究中合理应用指南。
Guide for judicious use of the paracetamol absorption technique in a study of gastric emptying rate of liquids.
作者信息
Sanaka M, Kuyama Y, Yamanaka M
机构信息
Department of Internal Medicine, School of Medicine, Teikyo University, Tokyo, Japan.
出版信息
J Gastroenterol. 1998 Dec;33(6):785-91. doi: 10.1007/s005350050177.
The paracetamol absorption technique, a widely used method for evaluating the gastric emptying rate of liquids, appears to be performed inappropriately, resulting from a lack of consideration of pharmacokinetics in paracetamol absorption. This review suggests that appropriate study designs and logical choice of the parameters for the rate of paracetamol absorption are the cornerstone of reliable investigation of gastric emptying using the paracetamol method.
对乙酰氨基酚吸收技术是一种广泛用于评估液体胃排空率的方法，但由于在对乙酰氨基酚吸收过程中未考虑药代动力学因素，该技术的应用似乎并不恰当。本综述表明，合适的研究设计以及对乙酰氨基酚吸收速率参数的合理选择是以对乙酰氨基酚法可靠研究胃排空的基石。
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