Young A S, Nuechterlein K H, Mintz J, Ventura J, Gitlin M, Liberman R P
Department of Psychiatry, University of California, Los Angeles, USA.
Schizophr Bull. 1998;24(4):629-34. doi: 10.1093/oxfordjournals.schbul.a033354.
The objective of this study was to predict suicidality in people with schizophrenia. Ninety-six patients with recent-onset schizophrenia were rated every 2 weeks for 1 year to examine (1) the temporal course of suicidal ideation and suicide attempts and (2) the extent to which anxiety, depression, and mild suicidal ideation were followed by significant suicidal ideation or a suicide attempt. The severity of suicidality changed rapidly. Low levels of suicidal ideation increased the risk for significant suicidal ideation or a suicide attempt during the subsequent 3 months. Depression was moderately correlated with concurrent suicidality, but not independently associated with future suicidality. Therefore, low levels of suicidal ideation may predict future suicidal ideation or behavior better than depressed mood in individuals with schizophrenia.
本研究的目的是预测精神分裂症患者的自杀倾向。96例近期发病的精神分裂症患者在1年时间里每2周接受一次评估，以考察：（1）自杀意念和自杀未遂的时间进程；（2）焦虑、抑郁和轻度自杀意念之后出现显著自杀意念或自杀未遂的程度。自杀倾向的严重程度变化迅速。低水平的自杀意念会增加在随后3个月内出现显著自杀意念或自杀未遂的风险。抑郁与同时期的自杀倾向呈中度相关，但与未来的自杀倾向并无独立关联。因此，对于精神分裂症患者，低水平的自杀意念可能比抑郁情绪能更好地预测未来的自杀意念或行为。
