Ruggeri M, Biggeri A, Rucci P, Tansella M
Servizio di Psicologia Medica, Università di Verona, Italy.
Psychol Med. 1998 Nov;28(6):1421-31. doi: 10.1017/s0033291798007466.
Short-term outcome of mental health care was assessed in a multidimensional perspective using graphical chain models, a new multivariate method that analyses the relationship between variables conditionally, i.e. taking into account the effect of antecedent and intervening variables.
GAF, BPRS, DAS (at baseline and after 6 months), LQL and VSSS (at follow-up only) were administered to 194 patients attending the South-Verona community-based mental health service. Direct costs in the interval were also calculated. Graphical chain models were used to analyse: (1) the associations between predictors (psychopathology, disability, functioning, assessed at baseline); (2) the effects of predictors on costs; and (3) the effect of predictors and costs on outcomes (psychopathology, disability, functioning, quality of life and service satisfaction) as well as their correlation.
Psychopathology, disability and functioning scores at baseline predicted the corresponding scores at 6-month follow-up, with greater improvement in the more severely ill. Higher psychopathology and poorer functioning at baseline predicted higher costs and, in turn, costs predicted poorer functioning at follow-up. Outcome indicators polarized in two groups: psychopathology, disability and functioning, which were highly correlated; and the dyad service satisfaction and quality of life. Service satisfaction was highly related to quality of life and was predicted by low disability and high dysfunctioning. No predictors for quality of life were found.
Graphical chain models were demonstrated to be a useful methodology to analyse process and outcome data. The results of the present study help in formulating specific hypotheses for future studies on outcome.
采用图形链式模型从多维视角评估精神卫生保健的短期结局,图形链式模型是一种新的多变量方法,可在考虑先行变量和中间变量影响的条件下分析变量之间的关系。
对194名接受南维罗纳社区精神卫生服务的患者进行了大体功能评定量表(GAF)、简明精神病评定量表(BPRS)、功能和症状评定量表(DAS,在基线和6个月后进行)、生活质量量表(LQL)以及仅在随访时进行的视觉模拟自评量表(VSSS)评定。还计算了这一期间的直接费用。使用图形链式模型分析:(1)预测因素(在基线时评估的精神病理学、残疾、功能)之间的关联;(2)预测因素对费用的影响;(3)预测因素和费用对结局(精神病理学、残疾、功能、生活质量和服务满意度)的影响及其相关性。
基线时的精神病理学、残疾和功能评分可预测6个月随访时的相应评分,病情越严重改善越大。基线时较高的精神病理学水平和较差的功能状态可预测较高的费用,而费用又可预测随访时较差的功能状态。结局指标分为两组:精神病理学、残疾和功能,它们高度相关;以及服务满意度和生活质量这一对指标。服务满意度与生活质量高度相关,且可由低残疾和高功能障碍预测。未发现生活质量的预测因素。
图形链式模型被证明是分析过程和结局数据的有用方法。本研究结果有助于为未来结局研究提出具体假设。