Ghosh P K, Gupta S, Naik S, Ayyagari A, Naik S R
Department of Gastroenterology, Immunology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Indian J Exp Biol. 1998 Sep;36(9):911-5.
Axenic E. histolytica trophozoite strain NIH:200 and HMI:IMSS when co-associated with aerobic bacteria Escherichia coli strain K12 and serotype 056 showed marked increase in virulence as observed by destruction of baby hamster kidney (BHK) monolayers. However, when incubated with anaerobic bacterial strains Clostridium perfringens and Bacteroides fragilis virulence remained unaltered. Further, adherence of E. histolytica to BHK monolayer was found to be mediated by N-acetyl-D-galactosamine.
无菌的溶组织内阿米巴滋养体菌株NIH:200和HMI:IMSS与需氧菌大肠杆菌菌株K12和血清型056共同培养时,如通过幼仓鼠肾(BHK)单层细胞的破坏所观察到的,毒力显著增加。然而,当与厌氧菌产气荚膜梭菌和脆弱拟杆菌一起培养时,毒力保持不变。此外,发现溶组织内阿米巴对BHK单层细胞的黏附是由N-乙酰-D-半乳糖胺介导的。