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[实验性与临床肺孢子菌病]

[Experimental and clinical pulmonary pneumocystosis].

作者信息

Lepekha L N, Barkhina T G, Parkhomenko Iu G

机构信息

Central Research Institute of Tuberculosis, Moscow.

出版信息

Arkh Patol. 1998 Sep-Oct;60(5):46-52.

PMID:9854613
Abstract

Rat lungs with hydrocortisone-induced pneumocystosis and a necropsy material from 5 patients with AIDS were studied light- and electron-microscopically. The identity of basic morphological features of lung pneumocystosis development in experiment and humans is demonstrated. Three main periods--latent, pronounced, terminal (pneumocystic pneumonia) are distinguished taking into account the relation of productive and vegetative forms of Pneumocystis carinii, state of the surfactants, type I alveolocytes and inflammation cells.

摘要

对患有氢化可的松诱导性肺孢子虫病的大鼠肺以及来自5例艾滋病患者的尸检材料进行了光镜和电镜研究。结果表明,实验性和人类肺孢子虫病发展的基本形态学特征具有一致性。考虑到卡氏肺孢子虫的增殖型和营养型的关系、表面活性剂的状态、I型肺泡细胞和炎症细胞,可区分出三个主要阶段——潜伏期、明显期、终末期(肺孢子虫肺炎)。

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