眼压作为假性剥脱性青光眼和原发性开角型青光眼视野缺损的危险因素。
Intraocular pressure as a risk factor for visual field loss in pseudoexfoliative and in primary open-angle glaucoma.
作者信息
Teus M A, Castejón M A, Calvo M A, Pérez-Salaíces P, Marcos A
机构信息
Department of Ophthalmology, Príncipe de Asturias Hospital, University of Alcalá de Henares, Madrid, Spain.
出版信息
Ophthalmology. 1998 Dec;105(12):2225-9; discussion 2229-30. doi: 10.1016/S0161-6420(98)91220-9.
OBJECTIVE
To analyze the relationship between intraocular pressure (IOP) and visual field loss in patients with primary open-angle glaucoma (POAG) and in those with pseudoexfoliative glaucoma (PEXG).
DESIGN
A cross-sectional, observational study.
PARTICIPANTS
Thirty-one patients with PEXG and 31 patients with POAG that was newly diagnosed were included in this study.
MAIN OUTCOME MEASURES
The authors recorded the untreated IOP and the amount of the visual field loss, at presentation, in both study groups.
RESULTS
The authors found a significant relationship between IOP and visual field mean deviation (MD) index (P = 0.0001, r = 0.68) in PEXG but not in POAG eyes (P = 0.7).
CONCLUSION
The authors found that untreated IOP levels can explain the amount of visual field loss, as measured by the MD index, much better in patients with PEXG than in comparable patients with POAG. Thus, vulnerability of the optic nerve head to increased IOP appears to be different in these two diagnostic categories.
目的
分析原发性开角型青光眼（POAG）患者和假性剥脱性青光眼（PEXG）患者的眼压（IOP）与视野缺损之间的关系。
设计
一项横断面观察性研究。
参与者
本研究纳入了31例PEXG患者和31例新诊断的POAG患者。
主要观察指标
作者记录了两个研究组患者就诊时未经治疗的眼压和视野缺损量。
结果
作者发现PEXG患者的眼压与视野平均偏差（MD）指数之间存在显著相关性（P = 0.0001，r = 0.68），而POAG患者的眼睛则无此相关性（P = 0.7）。
结论
作者发现，未经治疗的眼压水平能够更好地解释PEXG患者相较于POAG患者中，通过MD指数测量的视野缺损量。因此，在这两种诊断类型中，视神经乳头对眼压升高的易感性似乎有所不同。
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