与新诊断、未经治疗的开角型青光眼患者视野损害程度相关的角膜因素
Corneal Factors Associated with the Amount of Visual Field Damage in Eyes with Newly Diagnosed, Untreated, Open-angle Glaucoma.
作者信息
Bolivar Gema, Sanchez-Barahona Cristina, Ketabi Samira, Kozobolis Vassilios, Teus Miguel A
机构信息
Department of Ophthalmology, University Hospital Principe de Asturias, Carretera Alcalá-Meco S/N, Alcalá de Henares, 28805, Madrid, Spain.
Department of Ophthalmology, University of Alcalá, Alcalá de Henares, Spain.
出版信息
Ophthalmol Ther. 2021 Sep;10(3):669-676. doi: 10.1007/s40123-021-00375-w. Epub 2021 Jul 19.
INTRODUCTION
The aim of this study was to evaluate the correlation between several ocular parameters (intraocular pressure [IOP], corneal biomechanical properties) and the visual field (VF) mean deviation (VF MD) in eyes with open-angle glaucoma (OAG).
METHODS
We conducted a cross-sectional, observational study in which we measured the IOP with Goldmann applanation tonometry, the central corneal thickness (CCT), and the corneal parameters obtained from the Ocular Response Analyzer® (ORA®) and the Corvis® ST non-contact tonometer, in newly diagnosed and treatment-naïve eyes with OAG, to investigate whether there was any correlation between these ocular parameters and the VF MD.
RESULTS
A total of 51 eyes were analyzed. A statistically significant correlation was found only between the VF MD and corneal hysteresis (CH) (P = 0.003, r = 0.16) and CCT (P = 0.03, r = 0.08).
CONCLUSIONS
These results demonstrate that CH and CCT are associated with the amount of VF damage in treatment-naïve OAG eyes.
引言
本研究旨在评估开角型青光眼（OAG）患者的几种眼部参数（眼压[IOP]、角膜生物力学特性）与视野（VF）平均偏差（VF MD）之间的相关性。
方法
我们进行了一项横断面观察性研究，使用戈德曼压平眼压计测量眼压，测量中央角膜厚度（CCT），并从眼反应分析仪®（ORA®）和Corvis® ST非接触眼压计获取角膜参数，对新诊断且未接受过治疗的OAG患者的眼睛进行测量，以研究这些眼部参数与VF MD之间是否存在任何相关性。
结果
共分析了51只眼睛。仅在VF MD与角膜滞后（CH）（P = 0.003，r = 0.16）和CCT（P = 0.03，r = 0.08）之间发现了具有统计学意义的相关性。
结论
这些结果表明，CH和CCT与未接受过治疗的OAG患者眼睛的VF损害程度相关。
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