Rice J, Resar L M
Department of Pediatrics, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA.
Am J Med Sci. 1998 Dec;316(6):401-3. doi: 10.1097/00000441-199812000-00009.
Influenza A is associated with leukopenia, although it is not reported to cause isolated thrombocytopenia, anemia, or pancytopenia. The authors report three pediatric patients with transient cytopenias associated with influenza A infection, all of whom had evidence for influenza A infection by direct immunofluorescence from nasopharyngeal aspirates. In all patients, cytopenias were transient and improved as their viral symptoms resolved. All patients improved spontaneously. This is the first report of transient pancytopenia, anemia, or thrombocytopenia associated with influenza A infection. Given the high frequency of influenza A infections during the winter months, it is important to recognize the associated hematologic findings.
甲型流感与白细胞减少有关，尽管尚无报道称其会导致单纯性血小板减少、贫血或全血细胞减少。作者报告了3例与甲型流感感染相关的儿童短暂性血细胞减少症患者，所有患者经鼻咽抽吸物直接免疫荧光检测均有甲型流感感染的证据。所有患者的血细胞减少均为短暂性，随着病毒症状的缓解而改善。所有患者均自发好转。这是首例关于与甲型流感感染相关的短暂性全血细胞减少、贫血或血小板减少的报告。鉴于冬季甲型流感感染的高发率，认识到相关的血液学表现很重要。
