Mahesh Dande Naga, Sreelatha B, Vinoth S, Nancy S
Department of Paediatrics, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation - Deemed to be University (VMRF-DU), Karaikal, Puducherry, India.
Department of Community Medicine, Vinayaka Mission's Medical College and Hospital, Vinayaka Mission's Research Foundation - Deemed to be University (VMRF-DU), Karaikal, Puducherry, India.
Bioinformation. 2024 Mar 31;20(3):252-257. doi: 10.6026/973206300200252. eCollection 2024.
Influenza infections in developing countries are under reported and WHO estimates that nearly 99% of influenza deaths worldwide occur in children under-five years of age in Asian and African countries. Consequently, this study aims to analyze the use of clinical profile and easily available laboratory parameters to aid identification of the possible viral etiology in the setting of pre-monsoon ILI. A cross-sectional study was carried out for three months among children with ILI attending fever clinic of a tertiary care hospital in Karaikal, South India. In the study population the prevalence of ILI was highest in the age group four to five years followed by school aged children. Adolescents were affected the least. Influenza B was most common virus causing ILI in this region, followed by covid-19 infection. Laboratory parameters depicted a significantly high ESR in COVID-19 infected ILI children. They also exhibited leucopenia and normal platelet counts. Clinical symptoms and laboratory parameters which are easily available and cheaper can be used in resource poor settings of healthcare to identify possible influenza and COVID-19 infected children amongst cases presenting with ILI.
发展中国家的流感感染报告不足,世界卫生组织估计,全球近99%的流感死亡发生在亚洲和非洲国家的五岁以下儿童中。因此,本研究旨在分析临床特征和易于获得的实验室参数的使用情况,以帮助在季风前流感样疾病的背景下确定可能的病毒病因。在印度南部卡拉伊卡尔一家三级护理医院的发热门诊,对患有流感样疾病的儿童进行了为期三个月的横断面研究。在研究人群中,流感样疾病的患病率在4至5岁年龄组最高,其次是学龄儿童。青少年受影响最小。乙型流感是该地区引起流感样疾病最常见的病毒,其次是新冠病毒感染。实验室参数显示,新冠病毒感染的流感样疾病儿童的血沉率显著升高。他们还表现出白细胞减少和血小板计数正常。在医疗资源匮乏的环境中,可以使用易于获得且成本较低的临床症状和实验室参数,在出现流感样疾病的病例中识别可能感染流感和新冠病毒的儿童。