Brawley O W, Knopf K, Merrill R
Office of Special Populations Research, National Cancer Institute, Bethesda, MD 20892, USA.
Semin Urol Oncol. 1998 Nov;16(4):187-92.
The incidence and mortality of prostate cancer is highly varied among populations and especially among blacks and whites. The incidence rates of all American populations have dramatically changed over the past 25 years. The recent increase in incidence has been attributed to prostate cancer screening. Although the incidence has increased over the past 25 years, the mortality rates although vastly different between populations have remained rather stable within populations. Prostate cancer is still a disease that primarily afflicts older men. The median age at diagnosis is 71 years for whites and 69 years for blacks. More than 80% are over the age of 65 years. Screening for prostate cancer has dramatically increased the number of men with local disease at diagnosis, but it is unclear whether screening and aggressive treatment have caused a decrease in mortality.
前列腺癌的发病率和死亡率在不同人群中差异很大，尤其是黑人和白人之间。在过去25年里，所有美国人群的发病率都发生了巨大变化。近期发病率的上升归因于前列腺癌筛查。尽管在过去25年里发病率有所上升，但不同人群之间死亡率差异极大，而在各人群内部死亡率却保持相当稳定。前列腺癌仍然是一种主要影响老年男性的疾病。白人的诊断中位年龄为71岁，黑人则为69岁。超过80%的患者年龄在65岁以上。前列腺癌筛查显著增加了诊断时患有局部疾病的男性数量，但尚不清楚筛查和积极治疗是否导致了死亡率的下降。
