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一名威尔逊病患者使用青霉胺治疗后肾病综合征的早期发作。

Early onset of nephrotic syndrome after treatment with D-penicillamine in a patient with Wilson's disease.

作者信息

Siafakas C G, Jonas M M, Alexander S, Herrin J, Furuta G T

机构信息

The Combined Program in Pediatric Gastroenterology and Nutrition, The Children's Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA.

出版信息

Am J Gastroenterol. 1998 Dec;93(12):2544-6. doi: 10.1111/j.1572-0241.1998.00715.x.

Abstract

Wilson's disease responds to a variety of treatments including D-penicillamine and trientene. Nephrotic syndrome is a late complication of D-penicillamine treatment. We report a pediatric patient with Wilson's disease who developed nephrotic syndrome 2 wk after beginning D-penicillamine. His nephrosis resolved and his disease is quiescent with trientene treatment.

摘要

肝豆状核变性对包括青霉胺和曲恩汀在内的多种治疗方法有反应。肾病综合征是青霉胺治疗的晚期并发症。我们报告了一名患有肝豆状核变性的儿科患者,在开始使用青霉胺治疗2周后出现了肾病综合征。他的肾病已缓解,且在使用曲恩汀治疗后病情处于静止状态。

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